MATHEMATICAL MODELLING OF HEPATITIS E REVEALING THE NEMESIS OF HUMAN MOBILITY
DOI:
https://doi.org/10.33003/fjs-2026-1007-4755Keywords:
Hepatitis E, Mathematical Modeling, Human Mobility, Reproduction NumberAbstract
The hepatitis E virus causes hepatitis E, which is an outbreak of the liver. It is enteric in origin and is primarily spread orally, although it can also be spread through contaminated food, drink, and excrement. This work developed a novel model to study the impact of human mobility on hepatitis E virus dynamics; the reproduction number was calculated using a new generation matrix. Further, we calculated the disease-free equilibrium point of the model. The derived model has been fitted using Nigerian hepatitis E data, and a few parameters have been estimated using these data. Local sensitivity analysis has been conducted on the effective reproduction number, revealing that treatment is effective at reducing it, and that the effective contact rate is the most sensitive to increasing it. In this work, a numerical simulation has also been done.
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Copyright (c) 2026 Agada Apeh Andrew, Kifayah Tomilola Alabi, James Andrawus, Rakiya Mohammed Ngoshe, Felix Yakubu Eguda, Danat Nanle, Oghenefejiro Akpodamure, Sunday Babuba, Bashari Abdullahi, Kefas Bitrus, Stephen Ishaya Maiwa, Oladele Yusuf Olatunji, Ballah Akawu Denue
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