STUDY OF THE HISTOLOGICAL AND BIOCHEMICAL EFFECT OF INSTANT NOODLES ON THE KIDNEY AND LIVER ON RATS MODEL

  • Mohammed Ibrahim
  • Rilwan Isah Tsamiya
  • Promise Oladipo
  • Bala Gaius
Keywords: Noodle, Wistar rat, Seasoning, Liver, Kidney

Abstract

Instant noodle is produced from flour, and sold in dried form in packets. The noodles are easy and quick in preparation to eat, it can also eat as snacks or as main food. The aim of this research is to investigate the effects of noodle with and without seasoning on the histology as well as biochemical parameters of liver and kidney on rats’ model. Three groups of 5 Wistar rats were used, they were fed with noodle with and without seasoning for the period of 28 days. After 28 days the blood of rats was collected for biochemical analysis, the rats were also sacrificed, liver and kidney were removed for histological analysis. Histological results show only a little change in the architecture of the liver and kidney, but only small amount of fat droplet in liver section. The Liver and Kidney tests didn’t show any changes in their parameters, only little increase in urea level of the kidney. Conclusively from this research, it was revealed no much effect of consuming instant noodle in rat model.

References

Abraham, B., Fakhar, I., Tikaria, A., Hocutt, L., Marshall, J., Swaminathan, S. & Bornhorst, J. A. 2008. Reverse Pseudohyperkalemia In A Leukemic Patient. Clinical Chemistry, 54, 449-451. DOI: https://doi.org/10.1373/clinchem.2007.095216

Adebayo, J., Balogun, E. A. & Oyeleke, S. 2009. Toxicity Study Of The Aqueous Extract Of Tithonia Diversifolia Leaves Using Selected Biochemical Parameters In Rats. Pharmacognosy Research, 1.

Alcaide, M. Á., De La Poza, E. & Guadalajara, N. 2019. Assessing The Sustainability Of High-Value Brands In The It Sector. Sustainability, 11, 1598. DOI: https://doi.org/10.3390/su11061598

Benson, A. E. 2018. Battle Of The Substitutes: Indomie Vs Supreme Noodles.

Dahiru, D., Obi, O. & Umaru, H. 2003. Effect Of Hibiscus Sabdariffa Calyx Extract On Carbon Tetrachloride Induced Liver Damage. Biokemistri, 15, 27-33.

Daniel, E., Momoh, S., Friday, E. & Okpachi, A. 2014. Evaluation Of The Biochemical Composition And Proximate Analysis Of Indomie Noodle. Iinternational Journal Of Medical And Applied Sciences, 3, 166-175.

Doumas, B. T., Watson, W. A. & Biggs, H. G. 1971. Albumin Standards And The Measurement Of Serum Albumin With Bromcresol Green. Clinica Chimica Acta, 31, 87-96. DOI: https://doi.org/10.1016/0009-8981(71)90365-2

Drury, R. & Wallington, E. 1980. Carleton’s Histological Technique 5th Ed. New York: Churchill Livingstone.

Eweka, A. & Adjene, J. 2007. Histological Studies Of The Effects Of Monosodium Glutamate On The Medial Geniculate Body Of Adult Wistar Rats. Electrolytes Journal Of Biomedical Science, 22, 5. DOI: https://doi.org/10.4314/abs.v6i1.40690

Eze, G., Ehimigbai, A., Ezugwu, N. & Okafor, F. 2017. Morphological Changes Induced By Instant Noodles Food On Kidney Of Adult New Zealand Rabbits. Iqsr J Dent Med Sci, 16, 93-7. DOI: https://doi.org/10.9790/0853-1601029397

Gotoh, N. & Wada, S. 2006. The Importance Of Peroxide Value In Assessing Food Quality And Food Safety. Jaocs, Journal Of The American Oil Chemists' Society, 83, 473. DOI: https://doi.org/10.1007/s11746-006-1229-4

Gotoh, N., Watanabe, H., Osato, R., Iwasawa, A., Inagaki, K. & Wada, S. 2005. New Sight On The Possibility Of The Neurotoxic Behavior Affected By The Oxidized Compounds In Fats And Oils. Journal Of Oleo Science, 54, 397-405. DOI: https://doi.org/10.5650/jos.54.397

Hawk, P. B. 1914. Practical Physiological Chemistry, P. Blakiston.

Henry, R. J. 1974. Clinical Chemistry: Principles And Technics. (No Title).

Higgins, C. 2016. Urea And The Clinical Value Of Measuring Blood Urea Concentration. Acutecaretesting. Org, 1-6.

Hostetter, T. H. 2003. Prevention Of The Development And Progression Of Renal Disease. Journal Of The American Society Of Nephrology, 14, S144-S147. DOI: https://doi.org/10.1097/01.ASN.0000070150.60928.06

Khudhur, P. K., Hajee, S. I., Abdulkareem, S. M. & Rahman, L. Q. 2021. Evaluation Of Hemato-Biochemical Parameters, Body And Organ Weight And Reproductive Profile Changes In Response To Receiving Different Levels Of Indomie Noodles In Albino Rats. Indian Journal Of Pharmaceutical Sciences, 83. DOI: https://doi.org/10.36468/pharmaceutical-sciences.spl.239

Kim, M.-J., Shin, S.-N. & Kim, S.-K. 2000. Proximate Composition And Calorie Of Korean Instant Noodles. Korean Journal Of Food Science And Technology, 32, 1043-1050.

Published
2024-03-04
How to Cite
IbrahimM., Tsamiya R. I., Oladipo P., & GaiusB. (2024). STUDY OF THE HISTOLOGICAL AND BIOCHEMICAL EFFECT OF INSTANT NOODLES ON THE KIDNEY AND LIVER ON RATS MODEL. FUDMA JOURNAL OF SCIENCES, 8(1), 135 - 140. https://doi.org/10.33003/fjs-2024-0801-2257