PHYTOCHEMICALS AND ANTIMICROBIAL ACTIVITY OF BOSWELLIA DALZIELII STEM BARK AGAINST SOME CLINICAL ISOLATES

Authors

  • S. Balarabe
  • B. S. Aliyu
  • H. Muhammad
  • M. A. Nafisa

Keywords:

: Phytochemicals, extracts, Boswellia dalzielii, antimicrobial activity, fractions

Abstract

Plants have been used in traditional medicine to treat common human illnesses in our local communities. Crude aqueous and methanol extracts of Boswellia dalzielii stem bark were screened to investigate the phytochemicals responsible for its antimicrobial activity. The crude extracts and methanol extract fractions were used to conduct antimicrobial activity against some clinical isolates (Eschericia coli, Shigella dysenteriae and Salmonella typhi). Results of the antimicrobial activity showed that both methanol and aqueous extracts had activity against the clinical isolates with higher activity observed in the methanol extract against E. coli (16.670.96 at 500 mg/ml) and S. typhi (16.170.75 at 500 mg/ml). Bioassay of the partitioned methanol extract showed n-butanol had the best activity against the organisms and the n- butanol fractions were more active against E. coli (16.00±0.00), then S. dysenteriae (14.00±0.00) and least active against S. typhi (11.00±0.00) all at 50 mg/ml. The MIC of all the organisms for both methanol and aqueous extracts is 7.81 mg/ml but 15.63 mg/ml in methanol for S. dysenteriae and the MBC range between 7.81- 125 mg/ml in both extract for all the organisms. The results of this study therefore indicated that the plants’ stem bark contain potent phytochemicals which inhibited the growth of the tested clinical isolates which validate its continued use in traditional medicine to cure illnesses. 

References

Abubakar, A. S., Hamza, A. M., Tadda, S. A. and Lado, A. (2018). Variability in growth characters and anti-nutritional properties of sickle pod (Senna obtusifolia L.). FUDMA Journal of Science, 2(1): 12-16.

Anonymous (2016): How ‘Tafasa’ weed is fast becoming export commodity Available at: https://www.dailytrust.com.ng/news/great-green-wall/how-tafasa-weed-is-fast-becoming-export-commodity/131043.html.

Burton, G. W. (1952). Quantitative inheritance in grasses. 6th International Grassland Congress 1:277-283.

Choi, Y. G. C., Chen, H. W. and Duh, P. D. (1997). Extraction and identification of an antioxidative component from Jue ming Zi (Cassia tora L.). Journal of Agriculture and Food Chemistry, 46: 820-824. Dol.10.1021/jf970690z.

Doughari, J. H., El-Mahmood, A. M. and Tyoyina, I. (2008). Antimicrobial activity of leaf extracts of Senna obtusifolia (L). African Journal of Pharmacy and Pharmacology, 2(1): 7-13.

Duke, J. A. (2001). Handbook of Phytochemical Constituents of GRAS Herbs and other Economic Botany 38, no. 3: 342-349.

Hall, D. W. and Vandiver, V. V. (1996). Sicklepod. Available at: http: //hammock.ifas.ufl.edu/ txt/fairs/4924.

Hanson, C. H., Robinson, H. F. and Comstock, R. E. (1956). Biometrical studies of yield in segregating populations of Korean Lespedza. Agronomy Journal, 48: 268-272.

Harry-O’kuru, R. E., Payne-Wahl, K. L. and Busman, M. 2012. Medicinal components recoverable from Sicklepod (Senna obtusifolia) seed: Analysis of components by HPLC-MSn. Journal Chromatography Separation Techniques, S2:001. Doi:10.4172/2157-7064.S1-001.

Hassan, L. G., Umar, K. J. and Tijjani, A. A. (2007). Preliminary investigation on the feed quality of monechmacilliton seeds. Chemclass Journal, 4: 74.

Holm, L., Doll, J. Holm, E. Pancho, J. Herberger, J. (eds). (1997). World weeds natural histories and distribution. New York, USA: John Wiley and Sons, Inc.

Irwin, H.S. and Barneby, R. C. (1982). The American Cassinae. A synoptical revision of Leguminosae tribe Cassieaesubtribe Cassiinae in the New World. Memoirs of the New York Botanical Garden, 35: 252-255.

Johnson, H. W., Robinson, H.F. and Comstock, R.E. (1955). Estimates of genetic and environmental variability in soybean. Agronomy Journal, 47: 314-318.

Lush, J. L. (1940). Intra-sire correlation and regression of offspring on dams as a method of estimating heritability of characters. Proceedings of American Society for Animal Production, 33: 293-301.

Mackey, A. P., Miller, E. N., & Palmer, W. A. (1997). Sicklepod (Senna obtusifolia) in Queensland. Land Protection, Department of Natural Resources.

Owolabi J., Omogbai, E. K. I. and Obasuyi, O. (2007). Antifungal and antibacterial activities of the ethanolic and aqueous extract of Kigelia africana (Bignoniaceae) stem bark. African Journal of Biotechnology, 6(14): 882-85.

Parsons, W. T. and Cuthbertson, E. G. (1992). Noxious Weeds of Australia. Inkata Press, Melbourne, 692p.

Patil, U. K., Saraf, S. and Dixit, V. K. (2004). Hypolipidemic activity of seeds of Cassia tora Linn. Journal of Ethnopharmacology, 90: 249-252. DOI: 10.1016/j.jep.2003.10.007.

Published

2023-04-11

How to Cite

Balarabe, S., Aliyu, B. S., Muhammad, H., & Nafisa, M. A. (2023). PHYTOCHEMICALS AND ANTIMICROBIAL ACTIVITY OF BOSWELLIA DALZIELII STEM BARK AGAINST SOME CLINICAL ISOLATES. FUDMA JOURNAL OF SCIENCES, 3(3), 587 - 593. Retrieved from https://fjs.fudutsinma.edu.ng/index.php/fjs/article/view/1606

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