SYNTHESIS, CHARACTERIZATION AND ANTIMICROBIAL STUDIES OF Cu (II), and Ni (II)   COMPLEXES DERIVED FROM 2-HYDROXYBENZALDEHYDE AND 2 AMINOPYRIDINE

Ibrahim Sani; Sunusi Y. Hussaini; Ibrahim U. Kutama

doi:10.33003/fjs-2023-0701-1299

Ibrahim Sani Department of Chemistry, Kano University of Science and Technology, Wudil
Sunusi Y. Hussaini Department of Chemistry, Kano University of Science and Technology, Wudil
Ibrahim U. Kutama Department of Chemistry, Kano University of Science and Technology, Wudil

DOI: https://doi.org/10.33003/fjs-2023-0701-1299

Keywords: Antimicrobial activities, ligand, metal complexes, Schiff base, Antimicrobial activities, ligand, metal complexes, Schiff base

Abstract

Schiff base ligand derived from condensation of 2-hydroxybenzaldehyde and 2-aminopyridine have been prepared and used to synthesized Cu (II) and Ni (II) complexes, characterized by spectroscopic method (IR spectra). Conductivity, solubility test were determined. On the basis of the infrared studies, appearing of new band around 721 -762 cm^-1and 553- 443 indicate formation of v ( M- N ) and v (M –O ) confirming a coordination of ligand to the metal ion through oxygen and nitrogen atoms. The antimicrobial activities of the complexes was studied against the Staphylococcus aureus, Escherichia coli, Candida albican. The cupper complex showed higher activity than the Nickel complex and the ligand.

References

Alves, R,Silvada,C.Silvada, D and modulo L (2011)Schiff bases: A Short review of their antimicrobial activities. J.Ad.Re.2,1-8Bader,N.R;(2010) A review Rasayan J.Chem.3,660.

Cinerman Z,Snezana M, Nives G.Schiff bases derived from aminopyridines as spectrofluorimetric analytic reagents, Croat Chem Acta.2000;78: 85-96.

Cizar,S. and Angela, K. (2000): Co (II), Ni (II) and Cu (II) complexes of Bidentate Schiff Bases. Acta ChimSlov.47:178-185.

E.A.Elzahany,K.H. Hegab, S.K.H.Khalil, and K.N.S Youssef, Australian Journal of basic and applied science;2(2),210(2008).

G.Bringmann, M.Dreyer, J.H.Faber,P.W.Dalsgaard,D.Staerk and J.W.

Gupta, R.R; Kumar and Gupta, V (1998).Heterocyclic Chemistry 1.230-234

H.I.Ugras, I.Basaran,T. Kilic and Ucakir, J.Heterocyclic Chem;43,1679.(2006).

Sani, S. Kurawa, M.A and Siraj, I.T solid state synthesis, spectroscopic and x-ray studies of Cu(ii) Schiff base.

Qin W,Sha L, panunzio M, Biondis S,Schiff bases: A Short survey on an evergreen Chemistry Tool. Molecules.2013; 18: 12264-12289.

Nasser, M, Hosny, N.M and Dossoki,F.I(2008).Schiff base complexes derived from 2-Acetylpyridine, leucine and some metal chlorides: Their preparation, characterization and physical properties J.Chem. Eng. Data, 53, 2567-2572.G.Cozzi, (2004) Chemical society Reviews, 33, 7,410.

H.Sharghi and M.A.Nasseri,(2003), Bulletin of the chemical society of japan,76,1,137.

Jaroszewski,(2004), journal of Natural product,67,5,743.

Jesmin,M,AliM.M and khanam;J.A.(2010).Antitumour activities of some Schiff bases derived from benzoin,salicylaldehyde,amino phenol and 2,4 dinitrophenylhydrazine. Thai J.Pharm. sci.34, 20-31.

Prakash, A. and Adhikari,A.(2011)Application of Schiff base and their metal complexea, A review.International journal of Chem.Tech. Research, 3, 1891-1896.

S.Bairagi,A.Bhosale and M.N Deodhar, E.journal of chemistry,6(3)759(2009).

Sexena, P.N; Kumar, S. and Dhar,D.N(2009).Application of metal complexes of Schiff bases,a review.J.SCi.Ind.Res,68,181-18

Silva da,C.Modolo,L and Alves,R.(2011).Schiff bases: A short review of their antimicrobial activities J.Ad.Res,2,1-8.

SYNTHESIS, CHARACTERIZATION AND ANTIMICROBIAL STUDIES OF Cu (II), and Ni (II) COMPLEXES DERIVED FROM 2-HYDROXYBENZALDEHYDE AND 2 AMINOPYRIDINE

Abstract

References

Announcements

FUDMA Journal of Sciences - Vol. 8_2024 Call for Manuscript Submission