B-HEMATIN INHIBITION ACTIVITY OF THE METHANOL LEAF EXTRACT AND RESIDUAL AQUEOUS FRACTION OF FICUS ASPERIFOLIA

Authors

  • Ibrahim Doma Abdullahi Department of Pharmacology Bayero Univesity Kano
  • Abdullahi Hamza Yaro Department of Pharmacology and Therapeutics, Bayero University, Kano, Nigeria.
  • Mustapha Ibrahim Gudaji

DOI:

https://doi.org/10.33003/fjs-2024-0802-2161

Keywords:

Antimalarial, Chloroquine, Ficus asperifolia, Heme-polymerization

Abstract

Chemotherapy is still regarded as the major intervention in fighting the malaria scourge despite the recent introduction of malaria vaccine. Screening of medicinal plants provides opportunities for the discovery of the potential drug molecules. Ficus asperifolia (Miq) family Moraceae has been traditionally employed in the treatment of many diseases including pain, fever and malaria. The aim of this study was to examine the anitmalarial activity of both the methanol leaf extract (MEFA) and residual aqueous fraction of Ficus asperifolia (RAF) through the determination of their heme polymerization inhibition ability. The powdered leaf was extracted using 70%

Author Biography

Abdullahi Hamza Yaro, Department of Pharmacology and Therapeutics, Bayero University, Kano, Nigeria.

HOD Department of Pharmacology and Therapeutics, Bayero University, Kano, Nigeria.

Published

2024-04-30

How to Cite

Abdullahi, I. D., Yaro, A. H., & Gudaji, M. I. (2024). B-HEMATIN INHIBITION ACTIVITY OF THE METHANOL LEAF EXTRACT AND RESIDUAL AQUEOUS FRACTION OF FICUS ASPERIFOLIA. FUDMA JOURNAL OF SCIENCES, 8(2), 15 - 22. https://doi.org/10.33003/fjs-2024-0802-2161