ACUTE TOXICITY ASSESSMENT OF AQUEOUS LEAF EXTRACT IN MICE AND ITS IMPACT ON LIPID PROFILES AND HAEMATOLOGICAL PARAMETERS IN MALE WISTAR RATS: A STUDY of Jatropha tanjorensis J.L. ELLIS & SAROJA
References
Abbott, R. D., Wilson, P. W., Kannel, W. B., & Castelli, W. P. (1988). High-density lipoprotein cholesterol, total cholesterol screening, and myocardial infarction: The Framingham Study. Arteriosclerosis, 8(3), 207–211. DOI: https://doi.org/10.1161/01.ATV.8.3.207
Adebajo, A.C., Olayiwola, G., &Omobuwajo, O.R. (2004). The Antidiabetic Potential of Jatropha tanjorensis Leaves. Nigerian Journal of Natural Products and Medicine 8, 55–58. DOI: https://doi.org/10.4314/njnpm.v8i1.11817
Alladi, S., & Shanmugasundaram, K. R. (1989). Induction of hypercholesterolemia by supplementing soy protein with acetate-generating amino acids. Nutrition Reports International, 40(5), 893–899.
Ansari, R. A., Rabiu, K. M., Ayuba, V., &Omolabake, O. O. (2020). Review on Jatropha tanjorensis (Hospital too far); significance as an anti-anaemia plant. International Blood Research & Reviews, 11(4), 1-7. DOI: https://doi.org/10.9734/ibrr/2020/v11i430134
Arunachalam K, Sasidharan SP: General Considerations and Collection of Animal Blood. In: Bioassays in Experimental and Preclinical Pharmacology. Springer Protocols Handbooks. Humana, New York, NY. 2021. DOI: https://doi.org/10.1007/978-1-0716-1233-0
Chaachouay, N., & Zidane, L. (2024). Plant-Derived Natural Products: A Source for Drug Discovery and Development. Drugs and Drug Candidates, 3(1), 184-207. DOI: https://doi.org/10.3390/ddc3010011
Chigozie, O. O., Uzoma, N. O., Ikechukwu, U. R., & Ikechukwu, E. S. (2018). Nutritional composition of Jatropha tanjorensis leaves and effects of its aqueous extract on carbon tetrachloride-induced oxidative stress in male Wistar albino rats. Biomedical Research, 29(19), 3569-3576. DOI: https://doi.org/10.4066/biomedicalresearch.29-18-665
Ebe, N. U., & Chukwuebuka, E. V. (2019). Effects of ethanol root extract of Jatropha tanjorensis on haematological indices of male albino Wistar rats. European Journal of Biology and Medical Science Research, 7(1), 7-14.
Ebenyi, L. N., Yongabi, K. A., Ali, F. U., Ominyi, M. C., Anyanwu, C. B., Benjamin, E., &Ogbanshi, M. E. (2021). Effect of Aqueous Leaf Extract of Jatropha tanjorensis on parasitaemia and haematological parameters in mice infected with Plasmodium berghei, Nigerian Journal of Biotechnology (1), 146-153. DOI: https://doi.org/10.4314/njb.v38i1.17
Ebhohon, S. O., Emelike, A. P., Onyenze, C. C., Ikenna, J. C., &Ngwuta, C. R. (2024). Phytochemical Characterization and Toxicity Assessment of Acute and Sub-Acute Oral Administration of Aqueous Extract of Jatropha Tanjorensis Leaf. GVU Journal of Science, Health and Technology GVU J-SHT, 9(1), 113–136. https://doi.org/10.5281/zenodo.13381411
Ellis, J.L., & Saroja, T.L. (1962). A new species of Jatropha from South India. Journal of the Bombay Natural History Society, 58, 834.
Ewa-Udu, N. E., C. Nwanebu, F., Stanley, H. O., & W. Okereke, I. (2022). Antibacterial Screening of Jatropha tanjorensis against Escherichia coli, Staphylococcus aureus and Pseudomonas aeruginosa. International Journal of Pathogen Research, 10(4), 12–17. DOI: https://doi.org/10.9734/ijpr/2022/v10i430255
Francis, G., Makkar, H. P. S., Carle, R., Mittelbach, M., Wink, M., Martinez Herrera, J., Kodekalra, R., & Becker, K. (2021). Critique on conclusions regarding toxic compounds in Jatropha curcas kernel cake. Communications biology, 4(1), 1348. https://doi.org/10.1038/s42003-021-02869-6. DOI: https://doi.org/10.1038/s42003-021-02869-6
Frieldwald WT, Levy RI, Fredrickson DS: Estimation of the concentration of low-density lipoprotein cholesterol in plasma without use of the preparative ultracentrifuge: Clinical Chemistry manual of histology, (3rd ed.) New York.1972. DOI: https://doi.org/10.1093/clinchem/18.6.499
Hartog, M. G. L., Feskens, E. J. M., Hollman, P. C. H., Katan, M. B., & Kromhout, D. (1993). Dietary antioxidant flavonoids and risk of coronary heart disease: The Zutphen Elderly Study. The Lancet, 342(8878), 1007–1011. DOI: https://doi.org/10.1016/0140-6736(93)92876-U
Idu, M., Igbafe, G., &Erhabor J.O. (2014). Anti-Anaemic Activity of Jatropha tanjorensis Ellis & Saroja in Rabbits. Journal of Medicinal Plants Studies, 2, 64–72.
Igbinaduwa, P.O., Usifoh, C.O., & Ugwu, C.C. (2011). Phytochemical analysis and toxicological evaluation of the methanolic extract of Jatropha tanjorensis leaf. Journal of Pharmacy and Bioresources, 8(2), 86-91. DOI: https://doi.org/10.4314/jpb.v8i2.4
Imohiosen, O. (2023). Phytochemical and Biological Screening of Catholic Vegetable (Jatropha tanjorensis) Aqueous Extract in Bali, Taraba State, Nigeria. American Journal of Chemistry and Pharmacy, 2(2), 37–40. https://doi.org/10.54536/ajcp.v2i2.1602. DOI: https://doi.org/10.54536/ajcp.v2i2.1602
Kanekt, P., Jarvinen, R., Reunanen, A., &Maatela, J. (1996). Flavonoid intake and coronary mortality in Finland: A cohort study. British Medical Journal, 312(7029), 478–481. DOI: https://doi.org/10.1136/bmj.312.7029.478
Kumar, G. R. K., Bapat, V. A., & Johnson, T. S. (2012). Phorbol esters and other toxic constituents of Jatropha curcas L. In Jatropha: Challenges for a new energy crop (pp. 441-460). Springer New York. DOI: https://doi.org/10.1007/978-1-4614-4806-8_24
Laposata M, McCaffrey P. Clinical Laboratory Methods: Atlas of Commonly Performed Tests. In: M Laposata and P McCaffrey (eds.) McGraw Hill. 2022.
Lorke, D. (1983). A new approach to practical acute toxicity testing. Archives of Toxicology, 54, 275-87. DOI: https://doi.org/10.1007/BF01234480
Murray, M. T., & Pizzorno, J. (1998). Cholesterol. In Encyclopedia of Natural Medicine (2nd ed., pp. 347–400).
Ndem, J. I., Bassey, E. I., Effiong, B. O., Bassey, U. E., & Ini, S. D. (2019). Haematopoietic potential of Jatropha tanjorensis leaf extract in Plasmodium berghi-berghi-infected mice treated with Hippocrate aafricana root bark extract. Journal of Diseases and Medicinal Plants, 5(4), 69-73. https://doi.org/10.11648/j.jdmp.20190504.12 DOI: https://doi.org/10.11648/j.jdmp.20190504.12
Neergheen-Bhujun, V. S. (2013). Underestimating the toxicological challenges associated with the use of herbal medicinal products in developing countries. BioMed research international, 2013, 804086. DOI: https://doi.org/10.1155/2013/804086
Omoboyowa, D. A. (2021). Sterols from Jatropha tanjorensis leaves exhibit anti-inflammatory potential: In vitro and in silico studies. Bulletin of the National Research Centre, 45, 194. https://doi.org/10.1186/s42269-021-00658-z. DOI: https://doi.org/10.1186/s42269-021-00658-z
Omobuwajo, O.R., Alade, G.O., Akanmu, M.A., Obuotor, E.M., &Osasan, S.A. (2011). Microscopic and toxicity studies on the leaves of J. tanjorensis. African Journal of Pharmacy and Pharmacology, 5(1), 12 –17.
Omoregie, E.S., & Osagie, A.U. (2011). Effect of Jatropha tanjorensis Leaves Supplement on The Activities of Some Antioxidant Enzymes, Vitamins and Lipid Peroxida-Tion in Rats. Journal of Food Biochemistry 35, 409–424. DOI: https://doi.org/10.1111/j.1745-4514.2010.00392.x
Oyewole, I.O., &Akingbala, P.F. (2011). Phytochemical analysis and Hypolipidemic properties of Jatropha tanjorensis leaf extract. Eurpean Journal of Medicinal Plants 1(4), 180 –5. DOI: https://doi.org/10.9734/EJMP/2011/497
Pillai, P., Suresh, P., Mishra, G., & Annapurna, M. (2011). Evaluation of the acute and sub-acute toxicity of the methanolic leaf extract of Plectranthus amboinicus (Lour) Spreng in Balb C mice. European Journal of Experimental Biology, 1(3), 236–245.
Rizvi, S. A. A., Einstein, G. P., Tulp, O. L., Sainvil, F., & Branly, R. (2022). Introduction to Traditional Medicine and Their Role in Prevention and Treatment of Emerging and Re-Emerging Diseases. Biomolecules, 12(10), 1442. DOI: https://doi.org/10.3390/biom12101442
Srivastava, S., Virmani, T., Haque, M. R., Alhalmi, A., Al Kamaly, O., Alshawwa, S. Z., & Nasr, F. A. (2023). Extraction, HPTLC Analysis and Antiobesity Activity of Jatropha tanjorensis and Fraxinus micrantha on High-Fat Diet Model in Rats. Life (Basel, Switzerland), 13(6), 1248. https://doi.org/10.3390/life13061248. DOI: https://doi.org/10.3390/life13061248
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