SYNTHESIS AND CHARACTERIZATION OF SALICYLALDEHYDE AND 2,4-DINITROPHENYL HYDRAZINE SCHIFF BASE WITH ITS COBALT (II) AND MANGANESE (II) COMPLEXES
Abstract
The synthesis of Schiff base derived from salicylaldehyde and 2,4-dinitrophenyl hydrazine and its metal complexes were undertaken. This synthesis was achieved via the reflux condensation of salicylaldehyde and 2,4-dinitrophenyl hydrazine. Two metal complexes were prepared by coordinating the as-synthesized ligand with Cobalt (II) and Manganese (II) ions. The structures of the prepared ligand and the complexes were confirmed from the Fourier transformed infrared analysis. A laboratory tests were employed to study the melting and decomposition temperatures, Solubility, conductivity and magnetic susceptibility. The ligand obtained was a pale orange in colour with a percentage yield of 67% and melting point of 220ºC, The Cobalt(II) complex was found to be Orange in colour with 89% percentage yield and 250ºC decomposition temperature and the Manganese(II) complex was found to be a deep orange colour with 81% percentage yield and 246ºC decomposition temperature, The ligand and the complexes were found to be insoluble in water and slightly soluble in some common organic solvents, All the complexes are found to be paramagnetic in nature.
References
Ajibade Peter A. and Ikechukwu P. Ejidike.,( 2015). Synthesis, Characterization and BiologicalStudies of Metal (II) Complexes of (3E)-3-[(2-{(E)-[1-(2,4-Dihydroxyphenyl) ethylidene]amino}ethyl)imino]-1-phenylbutan-1-one Schiff Base. Journal of Chemical andPharmaceutical Research, (ISSN 1420-3049).
Aliyu,H.Nand Sani. U., (2012). Synthesis , characterization and biological activity of manganese ( II ), iron ( II ), cobalt ( II ), nickel ( II ) and copper ( II ) schiff base complexes against multidrug resistant bacterial and fungal pathogens. International Research Journal of Pharmacy and Pharmacology, 2(February), pp.40–44.
Babu, K.and Amutha, P., (2014). The new Cu ( II ) and Ni ( II ) complexes of schiff bases : Synthesis,characterization and antibacterial studies. Der Pharma Chemica,6(1), pp.432-435.
Brodowska, K. and Lodyga-Chruscinska, E., (2014). Schiff bases – interesting range of applications in various fields of science. CHEMIK, 68(2), pp.132–134.
Chacrabarti, P., (1993). Synthesis, characterization and antimicrobial studies of Cu (II) complexes with semicarbazone and salicylaldehyde. Journal of Molecular Biology., vol 234, p.463.Polish Journal of Chemistry, 625(79), pp.619–625.
Cotton, F.A and Wilkinson, J., (1962). “Advanced Inorganic Chemistry.” Journal of Advanced Research, 2nd edition (Interscience Publishers, New York), pp.124–129.
Fugu, M. B., Ndahi, N.P.. Paul, B.B. and Mustapha, A.N.,( 2013). “Synthesis, characterization, and antimicrobial studies of some vanillin Schiff base metal(II) complexes” Journal of Chemical and Pharmaceutical Research,. Journal of synthesis and Reaction in Metal Organic Chemistry, vol. 5(4), p.pp 22–28.
Gehad, Ahmed., (2006). Metal Complexes of Schiff Bases Preparation, Characterization, and Biological Activity _ Gehad Ahmed - Academia. , pp.361–382.
Gopu, P. and Xavier, A., (2015). Synthesis and Characterization of 4- ( 3-bromo-5- chloro-2-hydroxybenzlidimino ) Benzoic Acid and its Transition Metal Complexes. International Journal of Science and Research(IJSR), 4(8), pp.1491–1495.
Kumar, G., Devi, S.and Johari, R.,(2012). Synthesis and Spectral Characterization of Schiff Base Cr ( III ), Mn ( III ), and Fe ( III ) Novel Macrocyclic Complexes Derived from Thio- carbohydrazide and Dicarbonyl Compound. E-Journal of Chemistry, 9(4), pp.2255–2260. DOI: https://doi.org/10.1155/2012/956812
Kumar, N. and Sharma, P., (2013). Synthesis of New Schiff-Base Complexes and Their Applications. International Journal of Applied Research & Studies, II(2), pp.1–6.
Monika, T., and Sulekh, C., (2012). Synthesis, Characterization and Biocidal Properties of Platinum Metal Complexes Derived from 2,6-diacetylpyridine(bis thiosemicarbazone. open journal of inorganic chemistry, 3(1), pp.41–48. DOI: https://doi.org/10.4236/ojic.2012.23007
Raju, V.V. a nd Balasubramanian, K.P. (2011). Synthesis , spectral characterization , catalytic and biological studies of new Ru ( II ) carbonyl Schiff base complexes of active amines. Natural Science, 3(7):542–550. DOI: https://doi.org/10.4236/ns.2011.37076
Rehman, M., Imran, M. and Arif, M., (2013). Synthesis , Characterization and in vitro Antimicrobial studies of Schiff-bases derived from Acetyl acetone and Amino acids and their Oxovanadium ( IV ) complexes. American Journal of AppliedChemistry, 1(4), pp.59–66. DOI: https://doi.org/10.11648/j.ajac.20130104.13
Sharma, K.,Swami, M., Singh, R.,Fahmi, N. and Singh, R. V.,(2009). “Coordination chemistry of palladium(II) and Platium(II) complexes with bioactive Schiff bases: Synthetic, spectral, and biocidal aspects” Russian Journal of Coordination Chemistry,. Journal of Advanced Research, Vol.35(2), pp.pp142–148. DOI: https://doi.org/10.1134/S1070328409020092
Shelar Mahendra Devidas, Shujaat Hussain Quadri, Arjun Kamble, F.M.S. and D.Y.V., (2011). Novel one-pot synthesis of Schiff base compounds derived fromdifferent diamine and aromatic aldehyde catalysed by P2O5/SiO2 under free-solvent condition at room temperature . Journal of Chemical and Pharmaceutical Research, 3(2), pp.489–495.
Shushizadeh, M.R. and Azizyan, S.,( 2014). Solvent-Free Preparation of Novel 2- [ Phenyl ( Pyridine-2-Yl amino ) Methyl ] Phenols as Pseudo-Betti Processor for Natural Products. Jundishapur Journal of Natural Pharmaceutical Production, 9(4), pp.2–5. DOI: https://doi.org/10.17795/jjnpp-17808
Silva, J.F.M., Garden, S.J. and Pinto, A.C.,( 2001). The Chemistry of Isatins : a Review from 1975 to 1992 . Synthesis of Isatins. Journal of Brazilian Chemical Society, 12(3), pp.273–324. DOI: https://doi.org/10.1590/S0103-50532001000300002
Singh, Dharam P. A. L. Grover, Vidhi Kumar, and KrishanJain, Kiran., 2011. Synthesis and characterization of divalent metal complexes of the macrocyclic ligand derived from isatin and 1,2-diaminobenzene. Journal of the Searbian Chemical Society, 76(3), pp.385–393. DOI: https://doi.org/10.2298/JSC100607034S
Sonar, A.N., (2011). Acoustic and Volumetric properties of substituted hetrocyclic compounds in dioxane-water mixture at 303K. Journal of Chemical and Pharmaceutical Research, 3(4), pp.485–489.
Subramani, P., (2009). Characterisation of nickel ( II ) schiff base complexes derived from acetylacetone or salicylaldehyde with tripod amine. RASAYAN J.Chem, 2(4), pp.935–936.
Turki, A.A., Al-hazaam, H. and Abbas, A.F., (2013). Synthesis , Characterization and Computational Study of some New Schiff. Der Pharma Chemica, 5(5), pp.307–313.
Ummathur, M.B., (2007). Metal complexes of Schiff ’s bases derived from 3- ( arylazo ) -2 , 4- -pentanediones with 2-aminophenol and 2-aminothiophenol having novel structural features and unusual physico – chemical properties. Journal of the Searbian Chemical Society, 72(11), pp.1075–1084. DOI: https://doi.org/10.2298/JSC0711075K
Usharani, M., (2013). Pharmacological properties of Schiff base metal complexes derived from substituted pyridine and aromatic amine A REVIEW. International Journal of Pharmaceutical Sciences and Health Care, 5(3), pp.1–11.
Vinita, G., Sanchita, S. and Gupta, Y.K., (2013). Synthesis and Antimicrobial Activity of some Salicylaldehyde Schiff bases. Research Journal of Chemical Sciences, 3(9), pp.26–29.
Wadher, S. J. Karande, N. A. Borkar, D. S. and Yeole, P. G.,( 2009). Synthesis and biological evaluation of schiff bases of cinchophen as antimicrobial agents.International Journal of ChemTech Research, 1(4), pp.1297–1302.
Copyright (c) 2024 FUDMA JOURNAL OF SCIENCES
This work is licensed under a Creative Commons Attribution 4.0 International License.
FUDMA Journal of Sciences
