DETERMINATION OF THE PHYTOCHEMICAL CONSTITUENTS AND THE ANTIBACTERIAL ACTIVITY OF THE ROOT BARK EXTRACT OF NEOCARYA MACROPHYLLA (SABINE) PRANCE, AGAINST KLEBSIELLA PNEUMONIAE, AN EAR INFECTION-CAUSING PATHOGEN
Keywords:
Neocarya macrophylla, Klebsiella pneumoniae, Phytochemicals, AntibacteriaAbstract
Neocarya macrophylla root bark extractis a potential source of novel antimicrobial compounds, especially against Klebsiella pneumoniae, a bacterial pathogens. N. macrophylla is a medicinal plant commonly used in traditional medicine in Northern Nigeria to treat asthma, skin infections, treatment of wounds, pulmonary troubles, dysentery, inflammations and it is also used for the treatment of eye and ear infections.The susceptibility test results showed inhibition range of 15, 13, 11, 13 and 14mm for the NM, NM4, NM3, NM2 and NM1 respectively against test organism at 50mg/mL, and 09, 11, 09, 12 and 13mm for NM, NM4, NM3, NM2 and NM1 respectively at 25mg/mL, and finally -, 09, -, 09 and 09mm for NM, NM4, NM3, NM2 and NM1 respectively at 12.5mg/mL. This indicates NM, NM1, NM2 and NM4 to be the most active fractions against the organism at 50mg/mL in a respective manner and the least active fraction is NM3 at 25mg/mL, while fractions NM1, NM2 and NM4 showed no activity at 12.5mg/mL against the test organism. The test results indicated that root back extract of N. macrophylla has antibacterial potency and could be used as an alternative antimicrobial therapy
References
Abobi, S. M., & Ekau, W. (2013). Length-weight relationships and condition factors of Alestes baremose, Brycinus nurse and Schilbe intermedius from the lower reaches of White Volta River (Yapei), Ghana.
Abobi, S. M., Alhassan, E. H., & Asare, I. O. (2015). Analysis of the Fecundity and Gonadal stages of African carp, Labeo senegalensis (Valenciennes, 1842) from the White Volta, Ghana.
Abdullahi M.Y, Babatunde T., Abdulkarim B (2019). Reproduction biology, spawning cycle and age determination of Silverside (A. baremose, JOANIS, 1835) in Zobe Dam, Katsina State. MSc thesis Umaru Musa Yar’adua University, Katsina.
Apochi, J. O., Omeji, S., Adadu, M. O., & Kever, A. (2017). Length weight relationship, food and feeding habits and condition factor of Synodontis melanoptera and Synodontis courtetti from Lower River Benue, Benue State, Nigeria. Journal of Research in Forestry, Wildlife and Environment, 9(2), 73-82.
Bhatt, B. J., & Jahan, N. (2015). Determination of age and growth rate of fresh water fish Labeo rohita (Ham. 1822) by using cycloid scales. Int J Pure App Biosci, 3(3), 189-200.
Carlander KD (1969). Handbook of freshwater fishery biology. The lowa State University Press, Ames, IA. 1:752.
Dan-kishiya, A. S. (2018). Length-Weight Relationship and Condition Factor of Silver Catfish (Bagrus bayad Forskal, 1775) In Zobe Reservoir, Dutsinma Local Government Area, Katsina State, Nigeria. FUDMA JOURNAL OF SCIENCES-ISSN: 2616-1370, 2(1), 178-182.
Ezenwa, B. and Ikusemiju, K. (1981). Age and growth determinations in the catfish, C'hrysichthys nigrodigitants (Lacepede) by use of the dorsal spine. J. Fish Biol. 19: 345-351
Fagade, S. O. (1974). Age determination in Tilapia melanotheron (Rupeli) in the Lagos Lagoon, Nigeria. In: The Ageing of Fish (TB. Ragenal, Ed.). Proceedings of Symposium. 234pp. Ole Working: Unwin.
Froese, R. (2006). Cube law, condition factor and weight–length relationships: history, meta-analysis and recommendations. Journal of Applied Ichthyology 22:241–253.
Gayanilo, F. C. (1997). Fisat: FAO-ICLARM Stock Assessment Tools, Reference Manuals (No. 8). Food & Agriculture Org.
Imam, T. S., Bala, .U. Balarabe, M. L. and. Oyeyi T. I (2010). African Studies on Population and Health Printed in Nigeria Cifa technical paper, 10:43-103.
Kalita, L., Nazir, S., Ghosh, S. S., & Deka, P. (2016). Length-Weight relationship and relative condition factor of Nandus nandus (Hamilton, 1822) of Garjan Beel (wetland) of Assam, India. Intl. J of Biol. Res, 1(2), 36-39.
Muyideen Salawu (25 March 2010). "Water Scarcity - Commission Blames Inadequate Supply From Dam". Daily Champion. Retrieved2010-05-20.
Mzungu, I., Orpin, J. B., & Amos, B. (2017). The length weight relationship and condition factor of Schilbe mystus and Physico chemistry of water in Zobe dam Dutsinma, Katsina state. Chemistry, 1(1).
Ndimele, P. E., Kumolu-Johnson, C. A., Aladetohun, N. F. and Ayorinde, O. A. (2010). Length-weight relationship, condition factor and dietary composition of Sarotherodon melanotheron, Ruppell, 1852 (Pisces: Cichlidae) in Ologe Lagoon, Lagos, Nigeria. Agric. Biol. J. North Am., 1: 584- 590.
Ogbe, F. G., Ataguba, G. A., & Okosuwe, E. H. (2008). Feeding habits and growth parameters of Hydrocynus forskalii and Alestes nurse in River Benue, Nigeria. Journal of Applied Biosciences, 11, 576-583.
Ogbeibu AE (2005). “Biostatistics: A practical approach to research and data handlingâ€. Mindex Publishing Co. Ltd., Benin, Nigeria: 264.
Oso J. A. (2007) Ecological basis for the sustainable management of
Oreochromis niloticus (L) Sarotherodon galilaeus (L) and Clarias
gariepinus (Burchell 1822) in Ero Reservoir, Ikun Ekiti, Nigeria. Ph.D.
Thesis, University of Ibadan.
Otero, O., Pinton, A., Mackaye, H. T., Likius, A., Vignaud, P. and Brunet, M. (2010). The early/late Pliocene ichthyofauna from Koro-Toro, Eastern Djurab, Chad. Geobios, 43 (2), 241-251.
Pauly D. (1984). Length- converted catch curves. A powerful tool for fisheries research in the tropics. ICLARM Fishbyte; 2(3):9-10.
Pauly, D. (1993). Linear Regressions in Fisheries Research. Journal of the fisheries research, Canada, 30: 409-434.
Sagua, V. O. (1985). Studies on the biology of Gymnarchus niloticus in Lake Chad: Age determination and growth; meristic and morphometric characters
Vazzoler, A. D. M., & Vazzoler, G. (1965). Relation between condition factor and sexual development in Sardinella aurita (Cuv. & Val. 1847). Anais da Academia Brasileira de Ciências, 37, 353-359.
Willoughby, N. G. (1979). Some aspects of the ecology of Syndontis (Pisces Siluroidei) in Lake Kainji during its early years. Proceedings of the International Conference on Kainji Lake and River Basins Development in Africa, Ibadan, 11-17M December, 1977. Publ. and Printed by Kainji Lake Research Institute. 376
Published
How to Cite
Issue
Section
FUDMA Journal of Sciences
