PHYTOCHEMICAL SCREENING AND ANTIBACTERIAL ACTIVITY OF LEAVES EXTRACT OF SENNA OCCIDENTALIS (L.)

  • D. D. Musa
  • K. A. Bashir
  • K. Y. Hassan
Keywords: Senna occidenatalis, Phytochemical Screening, Extracts, Antibacteria

Abstract

Studies were carried out to determine the phytochemicals and the antibacterial activity of Senna occidentals, it is a shrub that grows between 5 to 8cm in height, it is an important member of the plant family Fabaceae and the subfamily Caesalpiniaceae and commonly found in the tropics. S. occidentalis leaves were collected in September, 2017 at flowering stage, the sample was air-dry at room temperature, the dried leaves were powdered and stored in an air-tight container for further use. The ethanolic, petroleum Ether and aqueous extracts were made by transferring 50g of the powder into 150ml of the solvents respectively and allowed to soak for four days; it was filtered using a filter paper. The results obtained from the research reveals that S.occidentalis contains certain phytochemicals such as anthraquinones, flavonoids, alkaloids, saponins, terpenoids, and Tannins which are responsible for the antibacterial activity of the plant; suggesting its potential use in the production of a new brand of antibiotic

 

References

Akinpelu, D.A. and Kolawole, D.O. (2004). Phytochemical and antimicrobial activity of leaf extract of Piliostigma thonningii (Schum.). Sci. Focus J. 7:64-70.

Cowan, Marjorie Murphy (1999). Clin. Microbiol. Rev 12(4):564. Bioproducts Processing. Article in press Cyperus rotundus (Cyperaceae). Afr. J. Biomed. Res. 9: 89-93.

Edoga, H. O., Okwu, D. E., and Mbaebie, B. O. (2005). Phytochemicals constituents of some Nigerian medicinal plants. African Journal Biotechnology, 4(7), 685–688.

El-Mahmood, A.M. and J.H. Doughari (2008). Phytochemical screening and antibacterial evaluation of the leaf and root extracts of Cassia alata Afr. J. Pharm. Pharmacol.2:124-129.

Faruq, U.Z., Hassan L.G., Manga B. S., Uba A., Olatunji M. K., Tal M.T. and Isiak F. S. (2006). Anti-bacterial activity of Cassia occidentalison Salmonella typhi. Proceedings of the 28th Annual International Conference Chemicals Society of Nigeria.pp. 177- 181

Harborne, J.B. (1973). Phytochemical Methods medicinal and aromatic plants. Trieste: ICS UNIDO. . Chapman and Hall Ltd.,

Idu, M.S.E., Omonigho and C.L. Igeleke (2007). Preliminary investigation on the phytochemistry of Senna alata L. flower. Pak. J. Biol. Sci., 10: 806-809.

Irobi, O.N., Moo-Young, M., Anderson, W.A. and Daramola, S.O. (1994). Antimicrobial activity of the bark of Brideliaferruginea (Euphobiaceae). Int. J. Pharmacol.34: 87-90.

Mohammed,Y., Nuhu, A.A. and Aliyu R., (2013). Effects of Cassia occidentalis aqueous leaf extract on biochemical markers of tissue damage in rats. Trop. J. Pharm. Res. 7(4): 1137- 1142.

Musa, D.D., Aliero, A.A and Bashir, K.A (2017) Preliminary allelopathic activity of aqueous leaf extract of Senna occidentalis on the Germination and early seedling growth of Cowpea int. Journal of Current Sciences and research 1(1): 23-25

Olorundare, E.E., Emudianughe T., khaar G.S. Kuteyi S. A. and Irobi D. N. (1992). Antibacterial properties of leaf extract of Cassia alata. Bio Res Com 4: 113-117

Pieme, C.A., V.N., Penlap B., Nkegoum C.L., Taziebou E.M., Tekwu F.X., Etoa and J. Ngongang (2006). Evaluation of acute and subacute toxicities of aqueous ethanolic extract of leaves of Senna alata (L.) Roxb (Ceasalpiniaceae). Afr. J. Biotechnol., 5: 283- 289.

Poongothai, A., Sreena, K.P., Sreejith, K., Uthiral Ingam M. and Annapoorani. S. (2011).

Preliminary phytochemical screening of Ficus racemesa Linn. Bark. Int. J. Pharma. Bio. Sci. Vol (2). Iss 2 Psychol Sci.; 20 (11):1388-93. doi: 10.1111/j.1467-9280.2009.02454.x. Epub 2

Russell, A.D. and Furr, J.R. (1977). The antibacterial activity of a new chloroxylenol preparation containing ethylenediamine tetra acetic acid. J. Appl. Bacteriol., 43: 253

Saidu, A.N., Aina, E.O., Mann A. and Leje, U.I. (2017). The effect of aqueous extract of Senna occidentalis leaves on rats infected with Salmonella typhi.

Satish, Kumar, Staib P. and White J. M., (2007). Optimization based automated curation of metabolic reconstructions. BMC Bioinformatics 8:212

Sathya, A. V., Ambikapathy and A. Panneer Selvamv (2012). Studies on the phytochemistry, antimicrobial activity and antioxidantproperties of Cassia occidentalis L. A.V.V.M. Sri Pushpam College, Poondi, Thanjavur, Tamilnadu, India 2 (4):530-533

Sharma, N., Trikha P., Athar M. and Raisuddin S. (2010). In-vitro inhibition of carcinogen induced mutagenicity by Cassia occidentalis and Emblica officianalis: Drug and chemical toxicology. 23:477-84

Sofowora, A. (1993). Medicinal Plants and Traditional Medicine in Africa. Spectrum Books Ltd., Ibadan, Nigeria, pp. 191-289.

Trease, G.E. and Evans W.C. (1989). Pharmacognosy, 11th edn. Bailliere Tindall, London pp. 45-50.

Usman, H., Abdulrahman F.I. and Ladan A.H. (2004). Phytochemical and Antimicrobial Evaluation of Tribulus terrestris L. (Zygophylaceae) growing in Nigeria. Res J Bio Sci.; 2:2447.

Vollekova, A.D., Kostalova and Sochorova R. (2000). Isoquinoline Alkaloids from Mahonia aquifolium stem bark is active against Malassezia Sp. Folia Microbiol. 2001; 46:107

Wang, Thind TS. Sardi, J. C. (2010) Potential and flux landscapes quantify the stability and robustness of budding yeast cell cycle network. Proc Natl Acad Sci U. S. A. 107(18):8 195-200

Wasagu, R.S.U., Hassan, S.W. and Lawal M. (2005). Evaluation of phytochemical and anti- oxidant levels and antimicrobial screening of aqueous leaf extract of Aloe vera (Aloe barbadensis Miller). Biological and Environmental Sciences Journal for the Tropics 2(2):21-25.

Published
2023-03-13
How to Cite
MusaD. D., BashirK. A., & HassanK. Y. (2023). PHYTOCHEMICAL SCREENING AND ANTIBACTERIAL ACTIVITY OF LEAVES EXTRACT OF SENNA OCCIDENTALIS (L.). FUDMA JOURNAL OF SCIENCES, 2(1), 59 - 65. Retrieved from https://fjs.fudutsinma.edu.ng/index.php/fjs/article/view/1260