ANTIMICROBIAL AND ANTIOXIDANT ACTIVITY OF SOME TRANSITION METAL COMPLEXES OF TWO LIGANDS DERIVED FROM AMINO ACIDS AND 2 – IMINO – 1 – METHYLIMIDAZOLIDIN – 4 – ONE

Authors

Keywords:

antioxidant; antimicrobial; metal complexes; amino acids; ligands.

Abstract

Plant extracts are most of the time used for antioxidant and antimicrobial studies. The Present study was designed to evaluate the activity of metal complexes as antioxidant and against some selected bacterial and fungal isolates. The new metal complexes of Cr (III) and Zn (II) containing ligands derived from Tyrosine, Leucine and 2 – imino – 1 – methylimidazolidin – 4 - one  were selected. The test compounds were evaluated for their possible antioxidant activity through free radical scavenging activity via using 1,1 – diphenyl – 2 – picryl – hydrazyl (DPPH) method. All the complexes exhibited good to moderate activity with Cr (III) complex (CrL1) and (CrL2) as the best radical scavengers having the % inhibition value of 67.74 and 65.33 respectively. The complexes were also screened for their antimicrobial activities against two bacterial isolates and one fungal isolate (Streptococcus pneumoniae, Klebsiella pneumoniae and Aspergillus niger). The result showed that all the compounds have the moderate activity against the tested organisms.

Author Biographies

Gwaram N.S

Department of pure and industrial chemistry. Senior Lecturer

Madaki U A

Depatrment of Biochemistry and Molecularbiology. Msc student

Dimensions

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Published

17-01-2022

How to Cite

ANTIMICROBIAL AND ANTIOXIDANT ACTIVITY OF SOME TRANSITION METAL COMPLEXES OF TWO LIGANDS DERIVED FROM AMINO ACIDS AND 2 – IMINO – 1 – METHYLIMIDAZOLIDIN – 4 – ONE. (2022). FUDMA JOURNAL OF SCIENCES, 5(4), 81-89. https://doi.org/10.33003/fjs-2021-0504-702

Issue

Vol. 5 No. 4 (2021): FUDMA Journal of Sciences - Vol. 5 No. 4

Section

Research Articles
Copyright & Licensing

How to Cite

ANTIMICROBIAL AND ANTIOXIDANT ACTIVITY OF SOME TRANSITION METAL COMPLEXES OF TWO LIGANDS DERIVED FROM AMINO ACIDS AND 2 – IMINO – 1 – METHYLIMIDAZOLIDIN – 4 – ONE. (2022). FUDMA JOURNAL OF SCIENCES, 5(4), 81-89. https://doi.org/10.33003/fjs-2021-0504-702

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