EVALUATION OF HEMATOLOGICAL PARAMETERS IN ALBINO RATS EXPOSED DERMALLY TO TANNERY EFFLUENT FROM CHALLAWA INDUSTRIAL ESTATE KANO, NIGERIA.

  • K. A. Bichi
  • B. B. Yusif
  • S. B. Mustapha
  • Y. U. Jibrin
  • P. S. Thomas
Keywords: Haematological, Tannery effluent, physicochemical, dermal

Abstract

The effects on haematological parameters of albino rats were evaluated to assess possible toxicity of tannery effluent. The study was carried out for 28 days. Forty (40) matured albino rats of both sexes were divided into four groups of 10 rats each. Group 1 is the control group, which were exposed dermally with normal water. Groups 2, 3 and 4 were exposed dermally at different concentrations of 100%, 50% and 25% of the effluent respectively. The result of the physicochemical analysis of the effluent shows that the physicochemical parameters were above the standard limit. Rats exposed to different percentages of the effluent showed significant decrease in the level of haemoglobin and packed cells volume. Red blood cell, white blood cell, mean corpuscular volume, mean corpuscular haemoglobin, mean corpuscular haemoglobin concentration, platelet and lymphocytes do not significantly decrease or increase.

References

Adegoke AO et al 2012, Effect of cassava based diet on some haematological parameters in albino rats fed petroleum contaminated diet, International Journal of Applied Research in Natural Products Vol. 5 (1),

Bhuiyan, et al. (2010) “Investigation of the Possible Sources of Heavy Metal Contamination in Lagoon and Canal Water in the Tannery Industrial Area in Dhaka, Bangladesh.†Environmental Monitoring and Assessment,.

Christopher E. Ekpenyong, et al., (2011): Hematological effect of chronic administration of ethanolic extract of Garcinia conruanaseed on rat Journal of Natural Products, Vol. 4: 173-176

Devi, S. and Singh, H. (1988). Axo-carmine induced haematological and bio-chemical change in albino Rat. J. Environ. Biol. 9(l): 21-25.

Eaton, D.L. and Klassen, C.D. (1996). Principles of toxicology. In: Klassen, C.D, (ed). Toxicology-The basic science of poison, 5th Edn., New Delhi: McGraw. pp.13-33.

Grubinger, V.P., Gutenmann, W.H., .Doss, G.J., Rutzke, M and Lisk, D.J. (1994) “Chromium in Swiss Chard Grown on Soil Amended with Tannery Meal Fertilizer.†Chemosphere 28.4: 717–720.

Hossain, A.M. et al. (2007): “Heavy Metal Concentration in Tannery Solid Wastes Used as Poultry Feed and The Ecotoxicological Consequences.†Bangladesh Journal of Scientific and Industrial Research 42.4: 397–416.

Jenkins, G.C; McCorrie, P; Forsberg, C.M and Brown, J.L (1980): Studies on the anaemia in rabbits infected with Trypanosoma brucei brucei 1: Evidence for haemolysis. Journal of Comparative Pathology, 90:107-121

Jenkins, R., Barton, J,. and Hesselberg, J. (2004): The Global Tanning Industry: a Commodity Chain Approach.†Environmental Regulation in the New Global Economy: the impact on industry and competitiveness: Edward Elgar Publishing 157–172.

Kean, T.T. and Vuanghao, J.H., (2012). Sub-acute oral toxicity study of ethanoic leaves extracts of strobilan thescrispus in rat. Asian pacific journal of tropical biomedicine. 7 (2) :45-47.

Larson, A., Haux, C. and Sjobeck, M. 1985. Fish physiology and metal pollution: Results and experiences from laboratory and field studies. Ecotoxicol. Environ. Safety. 9: 250-281

Möller, A. Müller, H. W. Abdullah, A. Abdelgawad, G. and Utermann, J. (2005): “Urban Soil Pollution in Damascus, Syria: Concentrations and Patterns of Heavy Metals in the Soils of the Damascus Ghouta.†Geoderma (124.1-2) 63–71.

MOYSÉS, F. S. et al. (2014): Exposition to tannery wastewater did not alter behavioral and biochemical parameters in Wistar rats. Physiology & Behavior, v. 129, pp. 160-166,.

Ovuru, S. S. and Ekweozor, I. K. E. (2004). Haematological changes associated with crude oil ingestion in experimental rabbits. African Journal of Biotechnology, 3: 346-348.

Praveena M., Sandeep V., Kavitha N. and Jayantha Rao K. (2013). Impact of Tannery Effluent, Chromium on Hematological Parameters in a Fresh Water Fish, Labeo Rohita (Hamilton) Research Journal of Animal, Veterinary and Fishery Sciences 1(6) 1-5.

Princewill-Ogbonna, I.L, Abagha O.J., and Ijioma, S.N. 2015. Haematological and Histopathological parameters of rats fed with Aerial yam (Dioscorea bulbifera). Comprehensive Journal of Food Science and Technology Research Vol. 2(2), pp. 09 – 16,

Pushaka J.D, Akyengo A, yakubu A and Adejube A.A.H (2015). Bioaccumulation of Heavy Metals in Fish Tillapia zilli and Bullfrog Pyxicephalus edulis from River Challawa Kano State Nigeria International Journal of Ecological Science and environmental Engeneering. Vol. 2, No. 4, 2015, pp 30-34.

Saadia R. Tariq, Munir H. Shah, N. Shaheen, A. Khalique, S. Manzoor, and M. Jaffar. (2005): “Multivariate Analysis of Selected Metals in Tannery Effluents and Related Soil.†Journal of Hazardous Materials 122.1-2 : 17–22.

Sharma, S., Kalpana, A., Shweta, S.V., Singh, P.K., Ramesh, S. and Sharma, K.P. (2007). Toxicity assessment of textile dye wastewater using swiss albino rats. Australian J. Ecotoxicol. 13: 81-85.

Shen, T. T. (1999). “Industrial pollution prevention, (ed)†2ndEdition, Springer, pp. 40.

SIQUEIRA, I. R.; VANZELLA, C.; BIANCHETTI, P.; RODRIGUES, M. A. S.; STÃœLP, S. (2011).Anxiety-like behaviour in mice exposed to tannery wastewater: the effect of photoelectrooxidation treatment. Neurotoxicology and Teratology, v. 33, n. 4, p. 481-484,

Song, Z,. Williams, C.J. and Edyvean, R.G.J. (2000):“Sedimentation of Tannery Wastewater.†Water Research 34.7: 2171–2176.

Ukpai, O. M. and Nwabuko, O. P. (2014). Effects on haematological parameters and pathology of internal organs of Trypanosoma brucei brucei infected albino rats. Nigerian Journal of Biotechnology. Vol. 27 : 8- 13

Veena, k., Navodita P., and M.C. Varma. (2013). Toxicity impact of Silk dye effluent on blood profile of Swiss albino mice Mus musculus. Journal of Academia and Industrial Research (JAIR) Volume 2,

Wachukwu, C. K., Dede, E. B., Ozoemena, C. C. and Amala, S. E. (2004): Effect of gasoline on blood and liver functions of albino rats (Ratus ratus). Journal of Medical Laboratory Science, 13 (1) :1 – 5.

Wepener, W.M. and Vuren, J.H.J. 1992. Effect of chromium at different pH values on the haematology of Tilapia sparrmanii. J. Comparative Biochem. Physiol. 161C (2): 375-381.

Published
2021-06-28
How to Cite
BichiK. A., YusifB. B., MustaphaS. B., JibrinY. U., & ThomasP. S. (2021). EVALUATION OF HEMATOLOGICAL PARAMETERS IN ALBINO RATS EXPOSED DERMALLY TO TANNERY EFFLUENT FROM CHALLAWA INDUSTRIAL ESTATE KANO, NIGERIA. FUDMA JOURNAL OF SCIENCES, 5(1), 372 - 376. https://doi.org/10.33003/fjs-2021-0501-580