HIGH SALT DIET REDUCES OVARIAN, UTERINE WEIGHT, AND FERTILITY INDEX IN FEMALE WISTAR RATS

Authors

  • Olufunke Onaadepo
    Department of Physiology, Faculty of Basic Medical Sciences, University of Abuja, Abuja
  • Victor Omere Idahosa
    Department of Physiology, Faculty of Basic Medical Sciences, University of Abuja, Abuja
  • Roqeeb Busayo Babawale
    2Department of Physiology, Faculty of Basic Medical Sciences, University of Ilesa, Ilesa, Osun State, Nigeria.
  • Nachamada Solomon Emmanuel
    Department of Human Physiology, Faculty of Basic Medical Sciences, College of Medical Sciences, Ahmadu Bello University, Zaria. Kaduna State, Nigeria.
  • Victor Olorunshola Kolawole
    Department of Physiology, Faculty of Basic Medical Sciences, University of Abuja, Abuja

Keywords:

High salt diet, Uterine weight, Ovarian weight, Fertility index

Abstract

Female reproductive health is highly sensitive to hormonal and environmental factors, and diet is a significant modifiable factor influencing reproductive outcomes. This study aimed to investigate the impact of high-salt diets on the weight and size of the uterus and ovaries in female albino Wistar rats. Forty-four (44) female albino Wistar rats weighing between 200 and 250 g were randomly assigned to four groups comprising 11 albino Wistar rats each. The designated control group was fed with a non-high salt diet ad libitum; the other groups were fed 2.5 %, 3.5 %, and 4.5 % NaCl diets, respectively. All albino Wistar rats in groups 2, 3, and 4 were fed the experimental diet for 6 weeks. The male albino Wistar rats were housed separately before mating and allowed access to rat chow and water. The study showed that a high salt diet resulted in a significant decrease in the weight of the ovaries, the weight of the uterus and the fertility index. These findings show the importance of dietary regulation in preserving reproductive function and mitigating the adverse effects of metabolic disturbances. Thus, a high salt diet could be detrimental to the female reproductive system.

Dimensions

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Published

16-07-2025

How to Cite

HIGH SALT DIET REDUCES OVARIAN, UTERINE WEIGHT, AND FERTILITY INDEX IN FEMALE WISTAR RATS. (2025). FUDMA JOURNAL OF SCIENCES, 9(7), 137-141. https://doi.org/10.33003/fjs-2025-0907-3671

Issue

Vol. 9 No. 7 (2025): FUDMA Journal of Sciences - Vol. 9 No. 7

Section

Research Articles
Copyright & Licensing

FUDMA Journal of Sciences

How to Cite

HIGH SALT DIET REDUCES OVARIAN, UTERINE WEIGHT, AND FERTILITY INDEX IN FEMALE WISTAR RATS. (2025). FUDMA JOURNAL OF SCIENCES, 9(7), 137-141. https://doi.org/10.33003/fjs-2025-0907-3671

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