ISOLATION OF SQUALENE FROM DICHLOROMETHANE EXTRACT OF CROTON NIGRITANUS LEAF

Authors

  • Abdullahi Muhammad Abdullahi
    Federal University of health sciences Azare Bauchi Nigeria
  • Olime M. Nkemakonam
    Department of Chemical Sciences Pen Resource University Gombe
  • Usman Garba
    Department of Chemistry Federal University of Agriculture Makurdi Benue state
  • Muhammad A. Mustapha
  • Muhammad I. Nazifi
  • Muhammad B. Usman
  • Umar M. Ibrahim

Keywords:

Isolation, Terpenes, Croton, Extraction, Spectroscopy

Abstract

A precursor of steroids with a variety of biological activities is squalene. The purpose of the study was to identify and describe the industrial/medical chemical found in Croton nigritanus. Using the solvents such as; dichloromethane, ethyl acetate, and n-hexane, the procedure entails a liquid-liquid extraction stage using the partition method and a solid-liquid extraction step using the maceration method. For separation and purification, gravity column chromatography (GCC) and thin-layer chromatography were employed. The isolated chemical's identity was determined using FTIR, 1H NMR and GC-MS spectroscopy. The inquiry successfully extracted and analyzed the major chemical compound which was identified as Squalene.

Author Biography

Abdullahi Muhammad Abdullahi

Department of Chemistry faculty of Basic Sciences Federal University of health sciences Azare Bauchi State Nigeria. Graduate Assistant 

Dimensions

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Published

30-04-2024

How to Cite

ISOLATION OF SQUALENE FROM DICHLOROMETHANE EXTRACT OF CROTON NIGRITANUS LEAF. (2024). FUDMA JOURNAL OF SCIENCES, 8(2), 212-216. https://doi.org/10.33003/fjs-2024-0802-2049

Issue

Vol. 8 No. 2 (2024): FUDMA Journal of Sciences - Vol. 8 No. 2

Section

Research Articles
Copyright & Licensing

FUDMA Journal of Sciences

How to Cite

ISOLATION OF SQUALENE FROM DICHLOROMETHANE EXTRACT OF CROTON NIGRITANUS LEAF. (2024). FUDMA JOURNAL OF SCIENCES, 8(2), 212-216. https://doi.org/10.33003/fjs-2024-0802-2049

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