GREEN BIOSYNTHESIZED SILVER NANOPARTICLES MEDIATED BY TRICHOSANTHES CUCUMERINA EXTRACT AND ITS BIOLOGICAL ACTIVITIES

Authors

Keywords:

antioxidant; nanoparticles; T. cucumerina; FTIR; green biosynthesized; anti-inflammatory activities

Abstract

Biosynthesized Nanoparticles especially from plants are a new research trend nowadays. In this study, green biosynthesis of silver nanoparticles (TCAgNPs) employing Trichosanthes cucumerina methanol leaf extract was realized. The antioxidant and anti-inflammatory activities of both the methanol extract of T. cucumerina and TCAgNPs were carried out and compared. Indomethacin and ascorbic acid were employed as a positive control for these activities respectively.  Fourier transform infrared spectroscopy (FT-IR) scanning electron microscopy (SEM) and Ultraviolet-visible spectroscopy were employed to characterize the formation of TCAgNPs. The TCAgNPs showed absorption bands at around 340-440 nm which is a distinctive band for Ag Nanoparticles and functional groups accountable for Ag nanoparticles synthesized by plants were noticed in the FTIR. TCAgNPs were spherical in morphology as seen from the SEM images.  TCAgNPs displayed better antioxidant and anti-inflammatory activities at 400 ug/ml (9.79±0.58) as compared with its polar extracts (7.74±0.58) but both the polar part (52.06±1.27) and TCAgNPs (61.72±2.54) were better in anti-inflammatory activity when compared with the positive control indomethacin (antiinflammatory) (48.30±0.23). This study revealed that AgNPs from plants can find germaneness in food, drugs, environmental sciences and drugs.

Dimensions

Adebooye OC. (2008). Phytoconstituents and antioxidant activity of the pulp of snake tomato (Tricosanthes cucumerina). African Journal of Traditional, Complimentary and Alternative Medicines. 2008;5(2):173-179.

Barbara K, Nora S. (2005) United States environmental protection agency (US EPA) Proceedings: Nanotechnology and the Environment: Applications and Implications. Progress Review Workshop III. Arlington, VA;1-8.

Bello Oluwasesan M., Abiodun B. Ogbesejana, Adewumi Oluwasogo Dada, Safiya Muhammad Jagaba, Bello Oluwatoyin E. (2020). Biosynthesis, Characterization and Biological Applications of Silver Nanoparticles using Celosia trigyna and Solanum nigrum Extracts: Neglected Vegetables in Nigeria. Discovery Phytomedicine, Vol. 7(2): 76-83 doi: 10.15562/phytomedicine.2020.123.

Bello Oluwasesan M., Abiodun B. Ogbesejana and Uduma A. Uduma (2018b). Launaea taraxacifolia; a Neglected Vegetable from Nigeria, its Anti-inflammatory and Antioxidant Activities. ChemSearch Journal 9(1): 9 – 12.

Bello Oluwasesan M., Abiodun B. Ogbesejana and Uduma A. Uduma (2018b) Launaea taraxacifolia; a Neglected Vegetable from Nigeria, its Anti-inflammatory and Antioxidant Activities. ChemSearch Journal 9(1): 9 – 12. 27.

Bello Oluwasesan M., Olubunmi Stephen Oguntoye, Adewumi Oluwasogo Dada, Oluwatoyin E. Bello, Tijjani Ali, Ahmad Abdullahi Alhaji, Oluwatosin Adeniyi (2019). Phytobiological Facilitated Production of Silver Nanoparticles from Selected Non-Cultivated Vegetables in Nigeria and Their Biological Potential. Turkish Journal of Pharmaceutical Science DOI: 10.4274/ tjps.10846.

Bello, O. M., Ibitoye T., & Adetunji, C. (2018). Assessing antimicrobial agents of Nigeria flora Journal of King Saud University – Science, doi.org/10.1016/j.jksus.2018.04.017.

Bello, O. M., Ogbesejana, A. B. and Tijjani, A. (2018c). Lipoxygenase (Lox) Inhibitory Activity of Leaves of Ceiba Pentandra (L.) Gaertn: A Neglected Vegetable from Nigeria. FUDMA Journal of Sciences, 2(2); 79-82.

Bello, Oluwasesan M., Ogbesejana, A. B. and Tijjani, A. (2018c). Lipoxygenase (Lox) Inhibitory Activity of Leaves of Ceiba Pentandra (L.) Gaertn: A Neglected Vegetable from Nigeria. FUDMA Journal of Sciences 2(2); 79-82.

Dana A., Ilse Z, Dingermann T., Müller W. E., Steinhilber D., Werz O. (2002) Hyperforin is a dual inhibitor of cyclooxygenase-1 and 5-lipoxygenase. Biochem Pharmacol 2002, 64: 1767–1775.

Filippo E, Serra A, Buccolieri A, Manno D. (2010). Green synthesis of silver nanoparticles with sucrose and maltose: Morphological and structural characterization. Journal of Non-Crystalline Solids. 356:344–350.

Hoag EG, Collins JB, Holcomb JL, Hoag JR, Nadagouda MN, Varma RS. (2009) Degradation of bromothymol blue using nano iron synthesized through greener method. J. Mater. Chem. 19:8671-8677.

Kotakadi, V.S., Gaddam, S.A., Subba Rao, Y., Prasad, T.N.V.K.V., Varada Reddy, A., Sai Gopal, D.V.R. (2014). Biofabrication of silver nanoparticles using Andrographis paniculata. European Journal of Medicinal Chemistry 73. https: //doi.org/10.1016/j.ejmech.2013.12.004.

MubarakAli, D., Thajuddin, N., Jeganathan, K., Gunasekaran, M., (2011). Plant extract mediated synthesis of silver and gold nanoparticles and its antibacterial activity against clinically isolated pathogens. Colloids Surf. B: Biointerfaces 85, 360–365.

Oguntoye S. Olubunmi, Bello Oluwasesan M., Emmanuel Opeyemi, Dada Adewumi Oluwasogo, Abdulmeen Hamid (2018). Acetylcholinesterase inhibition and antioxidant evaluation of polyphenolic fractions and oil from four melon seeds used as condiments in Nigeria. Carpathian Journal of Food Science and Technology 10 (1); 82-94.

Ojiako OA, Igwe CU. (2008) The nutritive, antinutritive and hepatotoxic properties of Trichosanthes anguina (Snake Tomato) fruits from Nigeria. Pakistan Journal of Nutrition. 2008;7(1):85-89.

Oyedapo O. O, Akinpelu B. A., Orefuwa S. O. (2004) Antiinflammatory effects of Theobroma cacao, L. root extract. J. of Tropical Med. Plants (Malaysia) 5(2): 161-166.

Oyedapo O. O., Akindele V. R., Okunfolami K. O. (1997) Effects of the extracts of Olax subcorpiodes and Aspilia Africana on bovine red blood cells. Phytotherapy Res. 1997, 11: 305-306.

Prasad TNVKV, Elumalai EK. (2011). Biofabrication of Ag nanoparticles using Moringa oleifera leaf extract and their antimicrobial activity. Asian Pac J Trop Biomed. 2011;1(6):439-442.

Shinde, U.A., Kulkarni K.R., Phadke A.S.; Nair A.M., Dikshit V.J., Saraf M. N. (1999) Mastcell stabilizing and lipoxygenase inhibitory activity of Cedrus deodara (Roxb.) Loud wood Oil. Indian J. Exp. Biol, 37(3): 258-261.

Sofowora, E. A. (1993). Medicinal Plants and Traditional Medicine in Africa. 2nd ed. Spectrum Books limited Ibadan, Nigeria, 9 (25): 289.

Trease, G. E. & Evans, W. C. (1989). A Textbook of Pharmacognosy, 13th ed. Bailliere Tindall Ltd, London, 134 pp

Zayed FM, Eisa WH, Shabaka AA. Malva (2012). Parviflora extract assisted green synthesis of silver nanoparticles. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy. 423–428.

Zhang, X.F., Liu, Z.G., Shen, W., Gurunathan, S., (2016). Silver nanoparticles: Synthesis, characterization, properties, applications, and therapeutic approaches. International Journal of Molecular Sciences 17:1534. https://doi.org/10.3390/ijms17091534.

Published

16-07-2021

How to Cite

GREEN BIOSYNTHESIZED SILVER NANOPARTICLES MEDIATED BY TRICHOSANTHES CUCUMERINA EXTRACT AND ITS BIOLOGICAL ACTIVITIES. (2021). FUDMA JOURNAL OF SCIENCES, 5(2), 519-525. https://doi.org/10.33003/fjs-2021-0502-665

Issue

Vol. 5 No. 2 (2021): FUDMA Journal of Sciences - Vol. 5 No. 2

Section

Research Articles
Copyright & Licensing

FUDMA Journal of Sciences

How to Cite

GREEN BIOSYNTHESIZED SILVER NANOPARTICLES MEDIATED BY TRICHOSANTHES CUCUMERINA EXTRACT AND ITS BIOLOGICAL ACTIVITIES. (2021). FUDMA JOURNAL OF SCIENCES, 5(2), 519-525. https://doi.org/10.33003/fjs-2021-0502-665

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