ANTIFUNGAL EVALUATION OF DICHROSTACHY cinerea (LEAVES AND STEM) EXTRACTS AGAINST SOME DERMATOPHYTES

Authors

  • Halima Isah Abdullahi
  • Muhammad Yusha'u

DOI:

https://doi.org/10.33003/fjs-2021-0502-654

Keywords:

Antifungal activity, Dichrostachy cinerea, Microsporum canis, Trichophyton terrestre, Trichophyton mentagrophytes and Trichophyton verrucosum

Abstract

This study was carried out to evaluate the antifungal efficacy of Dichrostachys cinerea extracts against some isolates of dermatophytic fungi. The powdered plant materials were extracted via soxhlet extraction technique using methanol, dichloromethane and petroleum ether as extraction solvents. The extracts were subjected to phytochemical screening for qualitative detection of plant secondary metabolites. The extracts were further tested for antifungal activity against human isolates of Microsporum canis, Trichophyton terrestre, Trichophyton mentagrophytes and Trichophyton verrucosum. The results of phytochemical screening showed the presence of some secondary metabolites including; alkaloids, tannins, saponins, glycosides and steroid. Antifungal activity testing indicated that all the extracts were active against the isolates tested with the exception of T. verrucosum. Pet ether extracts showed the least activity as reflected in the zone of inhibition (24 mm at 50 mg/ml), against the isolates compared to methanol (30 mm at 25 mg/ml) and dichloromethane (30 mm at 50 mg/ml) extracts. The findings of this study, indicated that the plant is a potential for the drug candidate for the treatment of dermatophytic diseases and support the claim for their traditional use against skin diseases

References

Abubakar, M. (2012) An Assessment of Men’s Role and Attitude Towards Family Planning in Zaria L.G. A, Kaduna State, Nigeria. Unpublished M.Sc.Thesis, Department of Geography, Ahmadu Bello University, Zaria.

Agele, S. O., Iremiren, G. O., and Ojeniye, S. O. (2000). Effects of tillage and mulching on the growth, development and yield of late-season tomato (Lycopersicon esculentum L.) in the Humid South of Nigeria. Journal of Agricultural Science, 13(4), 55-59.

Akinbile, L. A and Odebode, S.O. (2007) Determinants of Farmers Use of Sustainable Soil Conservation Practices in Osun State, Nigeria. American-Eurasian Journal of Sustainable Agriculture. Vol No. 1, pp 1-7.

Birte, J., Abaidoo, R., David, C., and Karl, S. (2008). Soil conservation in Nigeria: past and present on-station and off-farm initiatives. Soil and water conservation society, Ankeny, Iowa, U.S.A.

Dimelu, M. U., Ogbona, S. C., and Enwelu, I. A. (2012). Soil conservation practices among arable crop farmers in Enugu-agricultural zone, Nigeria: implication for climate change. AESON Proceedings, 17th Annual Conference, 140-145.

Dumaski, J., Peiretti, J., Benitis, R., McCarry, D., and Pieri, C. (2006). The paradigm of conservation tillage. Proceedings of World Association of Soil and Water Conservation, pp. 58-64.

Fapojuwo, O. E., Olawoye, J.E., and Fabusoro, E. (2012). Soil Conservation Techniques for Climate Change Adaptation among ArableJournal of Agricultural Science and Technology. Crop Farmers in Southwest Nigeria. Journal of Agricultural Science and Technology. 12(2), 35-46.

Food and Agriculture Organization (FAO), (2014). The State of Food Insecurity in the World 2014:Strengthening the Enabling Environment for Food Security and Nutrition. Rome, FAO. Available online at http://www.fao.org/3/a-i4030e.pdf

Intergovernmental Panel on Climate Change IPCC (2007). Climate Change Synthesis Report. Contribution of Working Groups I, II & III to the Fourth Assessment Report. Geneva.

Javad, R. Hassan, K. and Esmaeil, H. (2014), Assessment of the Effect of Land Use Changes on Soil Physicochemical Properties of Jafarabad of Golestan Province, Iran. Bulletin of Environment, Pharmacology and Life Sciences. Vol 3 spl III. 296-300.

Kaduna State Government (2015). Agriculture Sector Performance Report 2014. Ministry of Economic Planning.

Kreicie, R.V. and Morgan, D.W. (1970). Determining Sample Size for Research Activities. Educational and Psychological Measurement, 30, 607-610.

Lin, L., Cao, M., Y., and Baskin, J. M., (2006). Non-constituent Species in Soil Seed Banks as Indicators of Anthropogenic Disturbance in Forest Fragments. Canadian Journal of Forest Research 36, pp. 2300-2316.

Matson PA, Parton WJ, Power AG, Swift MJ (1997). Agricultural intensification and ecosystem properties. Science 277:504–509. doi:0.1126/science.277.5325.504

National Population Commission (NPC) (2009). 2006 National Population Census report. National Population Abuja, Nigeria. March, 2009.

National Population Commission (NPC) (2009). Provincial Census Figure by States and Local Government in Nigeria. National population Commission, Abuja.

Ogunleye, E.K. (2006). Utilisation of Remote Sensing Products in Kaduna State: A Case Study of Kaduna and Zaria Metropolises. Unpublished PGD Project. Department of Geography and Regional Planning, Ambrose Alli University, Ekpoma, Edo State 3-10.

Olaitan, S.O and Omomia, O.A. (2006) Round-up Agricultural Science; A Complete Guide. Lagos: Longman Nigerian PLC. In Dimelu, M. U., Ogbona, S. C., and

Enwelu, I. A. (2012). Soil conservation practices among arable crop farmers in Enugu-agricultural zone, Nigeria: implication for climate change. AESON Proceedings, 17th Annual Conference, 140-145.

Pla, I. (2014). Advances in soil conservation research: challenges for the future. Journal of Soil Science, 4(3), 265-282.

Recha, J., Kapukha, M., Wekesa, A., Shames, S., and K. Heiner. (2014). Sustainable Agriculture Land Management Practices for Climate Change Mitigation: A training guide for smallholder farmers. Washington, DC. EcoAgriculture Partners.

Reidsma P, Tekelenburg T, van den Berg M, Alkemade R (2006). Impacts of land-use change on biodiversity: an assessment of agricultural biodiversity in the European Union. Agric Ecosyst Environ 114:86–102. doi:10.1016/j.agee.2005.11.026

Rigby D, Woodhouse P, Young T, Burton M (2001). Constructing a farm level indicator of sustainable agricultural practice. Ecol Econ 39:463–478. doi:10.1016/S0921-8009(01)00245-2

Sani, A.S. and Suleiman, S. (2017) Spatial Analysis of Traffic Hotspots in Zaria, Kaduna State, Nigeria. Yaradua University Journal of Sociology (YUJOSO). Vol. 1, No. 2.pp 141-148.

Smith, B., and Smithers, J. (2006). Adoption of soil conversation practices an empirical analysis in Ontario, Canada. Land Degradation and Rehabilitation, 3, 1-4.

Suleiman, U.B., Abdulhamed, A.I., Musa, I.J.and Yelwa, S.A (2019). Decadal Analysis and Estimation of Temperature Changes in Northern Senatorial Zone of Kaduna State-Nigeria. FUDMA Journal of Sciences (FJS). Vol.3 No.3 pp509-518.

Umar, S. (2012). Shika Dam Stability. An Unpublished Undergraduate Project submitted to the Department of Physics, Kaduna State University, Kaduna, Nigeria.

Wright, S.B. and McCurry, P. (1970): Geology. In Mortimore, M.J. (eds) (1970). Zaria and Its Region Occasional paper No. 4 Department of Geography A.B.U., Zaria. Pp. 5-12.

Published

2021-07-13

How to Cite

Abdullahi, H. I., & Yusha’u, M. (2021). ANTIFUNGAL EVALUATION OF DICHROSTACHY cinerea (LEAVES AND STEM) EXTRACTS AGAINST SOME DERMATOPHYTES. FUDMA JOURNAL OF SCIENCES, 5(2), 489 - 497. https://doi.org/10.33003/fjs-2021-0502-654