EFFECT OF AQUEOS EXTRACT OF Momordica balsamina AND Cucumis metuliferus FRUITS ON NEWCASTLE DISEASE IN PULLETS
The study was conducted to determine the effect of aqueous extract of Mormordica balsamina and Cucumis metuliferus fruits on Newcastle disease (NCD) in pullets. Ninety (90) pullets were used for the study. The pullets were divided into prophylactic and curative groups comprising 10 birds per group. For prophylactic groups aqueous extract of the fruits at concentration of 2.5g and 5.0g per 100litres of water were given to the pullets ad-libitum for two weeks and then challenged with Newcastle disease virus kudu 113 strain via intra ocular route while for curative groups the pullets were challenged with the virus and then treated with the aqueous extracts of the fruits at 2.5g and 5.0g per 100litres of water ad-libitum. Data collected were analyzed using one way analysis of variance (ANOVA) using Statistical Analysis Software version 9.1. The results showed that M. balsamina at 2.5g/100litres of water had very good curative abilities which recorded lower clinical signs, mortality, postmortem lesions, higher antibody titer and higher white blood cell activity with a statistically significant (p<0.05) association while the same fruit at 5.0g/100litres of water had the best results for prophylactic treatments recording least clinical signs and mortality rates and highest antibody titers, highest white blood cell count which was statistically significant (P<0.05). It is therefore recommended that Mormodica balsamina can be recommended at 2.5g/100litres and at 5g/100liters of water for the control and prevention of Newcastle disease respectively to farmers and that further studies should be carried out to establish optimum concentration levels for
Agang D., Abdu P.A., Saidu L. and Suleiman M.M. (2019). Evaluating the effect of Momordica balsamina linn, selenium and lamivudine for the treatment Newcastle disease in pullets. International Journal of Agricultural Research and Food Technology. 4(3): 255-264
Agang, I. (2014). Evaluating the effect of Momordica balsamina Linn, Selenium and Lamivudine for the treatment of Newcastle Disease in pullets. M.Sc. project. Ahmadu Bello Univercity Zaria.
Alawa, C.B.I., Adamu, A.M., Gefu, J.O., Ajanusi, O.J., Abdu, P.A., Jagun, A.G., Lamidi, O.S. and Oni, O.O. (2008).Ethnoveterinary practices in Nigeria: Survey of plants used as anthelmintics. Vom Journal of Veterinary Science. 5(1):2-11.
Alexander, D.J. (2003). Newcastle disease and other avian paramyxovirida infections. In: Diseases of Poultry, Saif, Y.M., Barnes, H. J., Glisson, Jr., Fadly AM., McDougal, L .R. and Swayne, D.E., 11th Ed, (Jordan, F. T. W.M., Patttison, M. Eds.). Pp. 64-87.
Alhaji Bishir Almu (2017). Personal communication, 20-09-2017, 10:30am
Allan, W.H., Lancaster, J. E. and Toth, B. (1978). Newcastle Disease Vaccines. Food and Agriculture. Organization of the United Nations , Rome, Italy.
Ati, O.F. Iguisi E.O. and Mohammed S.O. (2010). Effects of El Nino/Southern Oscillation (ENSO) on rainfall characteristics in Katsina, Nigeria. The African Journal of Agricultural Research, 5 (23): 3273-3278
Beloin, N., Gbeassor, M., Akpagana, K..Hudson, J., De Soussa, K., Koumaglo, K. and Arnason, J. T. (2005)."Ethnomedicinal uses of Momordica charantia (Cucurbitaceae) in Togo and relation to its phytochemistry and biological activity". Journal of Ethnopharmacology 96:49â€“55.
Benzioni A., Mendlinger A., Ventura M. and Huyskens S. (1993). Germination, fruits development, yield and post harvest characteristics of Cucunis metuliferus. In Janick J., Simon J.E. (eds), New Crops. Wiley, New York, Pp. 553-557.
Bukar-Kolo Y.M, Ibrahim U.I. and Abubakar B.U. (2006). A survey of major constrains limiting commercial poultry production in and around Gombe metropolis. Nigerian Veterinary Journal. 27 (2): 75-78
Burkill, H.M. (1985). Useful Plants of West Tropical Africa.Vol.1, 2nd ed. Royal Botanic Gardens, London. Pp.570-605
Camporese, A., Balick, M.J., Arvigo, R. Esposito, R.G., Morsellino, N., De Simone, F. and Tubaro, A. (2003). Screening of antibacterial activity of medicinal plants from Belize (Central America). Journal of Ethnopharmacology 87:103- 107.
Enslin, P.R., Joubert, T.G. and Rehm, S. (1954). Bitter principles of the CucurbitaceaeII .Paper chromatography of bitter principle research. Journal of South African Chemical Institute. 7:131- 138.
Evans W.C. (2009) Trease and Evans Pharmacognosy. Elsevier Health Sciences. Pp125
Gedif T. and Hahn H. (2003). The use of medicinal plants in self-care in rural central Ethiopia. Journal of ethnopharmacology. 87(2-3):155-61.
Guarrera, P., Forti, G. and Marignoli, S. (2005). Ethnobotanical and ethnomedicinal uses of plants in the district of Acquapendente (Latium, Central Italy). Journal of ethnopharmacology. 96. 429-44. DOI: https://doi.org/10.1016/j.jep.2004.09.014
Gupta, M.P, SolÃs, P.N., CalderÃ³n, A.I., Guinneau-Sinclair, F., Correa, M., Galdames, C.,Guerra, C., Espinosa, A., Alvenda, G.I., Robles, G. and Ocampo, R. (2005). Medical ethnobotany of the Tribes of Bocas del Toro, Panama. Journal of ethnopharmacology. 96:389-401.
Harsha, V.H., Hebbar, S.S., Shripathi, V. and Hegde, G.R. (2003). Ethnomedicobotany of Uttara Kannada district in Karnataka, India-plants in treatment of skin diseases. Journal of ethnopharmacology. 84:37-40.
Hassan, L.G & Umar, Kabiru Jega. (2006). Nutritional Value of Balsam Apple (Momordica balsamina L.) Leaves. Pakistan Journal of Nutrition. 5(10)522.529.
HernÃ¡ndez, T., Canales, M., Avila, J.G., Duran, A., Caballero, J., Romo de Vivar, A. and Lira A. (2003). Ethnobotany and antibacterial activity of some plants used in traditional medicine of ZapotitlÃ¡n de lasAlinas, Puebla (Mexico). Journal of ethnopharmacology. 88:81-188.
Ibrahim,U. I. and Tanya, S. N. (2001) : Prevalence of antibodies infectious bursal disease (illD) in village chickens in Sahel Zone of Nigeria. Bulletin of Animal Health production Africa. 49: 150-152.
Isah, 2009. Combating water scarcity in Katsina. Retrieved 20 may, 2010 from http,//www.wikipedia.org/wiki/Dutsinma.
Lawrence, D.R. and Bennett, P.N., (1995). Clinical Pharmacology ELBS with Churchill Livingston, Edinburgh. Pp 686.
Mgbojikwe A.C., Okpara J., Umera A.E., Aguiyi J.C. (2019). Effect of the Pulp Extract of Balsam Fruit (Momordica balsamina) on Avian Newcastle Disease Virus. American Journal of Biomedical Science and Engineering. 5(1): 1-7.
Nandagopalan, V., Anand, S.P., Prabha, L., Selvakumar, U. and A., Doss. (2011). An ethnobotanical study in the Pudukkottai District, South India. Asian Journal of Experimental Biological Sciences. 2: 412-421.
Rabe, T. and van Staden, J. (1997). Antibacterial activity of South African plants used for medicinal purposes. Journal of ethnopharmacology. 56:8187.
Raza, A., Muhammad, F., Bashir, S., Anwar, I., Awais, M.M., Akhtar, M., Aslam, B., Khaliq, T. and Naseer, M. (2015). Antiviral and immune boosting activities of different medicinal plants against Newcastle disease virus in poultry. World's Poultry Science, Journal. 71. 523-532. DOI: https://doi.org/10.1017/S0043933915002147
Ritch-Krc, E.M., Thomas, S., Turner, N.J. and Towers, G.H.N. (1996). Carrier herbal medicine: traditional and contemporary plant use. Journal of ethnopharmacology. 52:85-94.
Ritch-Krc, E.M., Thomas, S., Turner, N.J. and Towers, G.H.N. (1996). Carrier herbal medicine: traditional and contemporary plant use. J. Ethnopharmacol. 52:85-94. 64.
Roodt, V. (1998).Common wild flowers of the Okavango Delta; medicinal uses and nutritional value. The shell Field Guide Series: Part II.
Salami, J.O., Egbulett, B.N., Kwaga, J.K.P., Yusufu, H.I. and Abdu, P.A. (1989). Disease diagnosed in poultry in Kaduna State, Nigeria. Bulletin of Animal Health and Production in Africa, 18: 123-125.
Semple, S.J., Reynolds, G.D., Oâ€™Leary, M.C. and Flower, R.L.P. (1998).Screening of Australian medicinal plants for antiviral activity. Journal of ethnopharmacology. 60:163- 172.
Sinclair, S. (1998). Chinese herbs: a clinical review of Astragalus, Ligusticum, and Schizandrae. Alternative Medicine Review. 3:338â€“344.
Sofowora, A., Ogunbodede, E. and Onayade A. (2013) The Role and Place of Medicinal Plants in the Strategies for Disease Prevention. African Journal of Traditional and Complementary Alternative Medicine. 10(5):210-229 DOI: https://doi.org/10.4314/ajtcam.v10i5.2
Verma, K.C., Panisup, A.S., Kataria, J.M., Singh, S. and Mohanty, G.C. (1985). AModified Vaccination Regimen for the Control of Ranikhet (Newcastle) Disease in Chickens. Indian Journal of Poultry Science 20: 231-235
Wakamatsu, N., king, D.J., Seal, B.S., Samal, S.K and Brown, C.C. (2006). The Pathogenesis of Newcastle disease. A comparison of selected Newcastle disease virus wild-type strains and their infectious clones. Virology, 353:333-343.
YeÅŸilada, E., Sezik, E., Honda, G., Takaishi, Y., Takeda, Y. and Tanaka T. (1999) Traditional Medicine in Turkey IX: Folk Medicine in North-West Anatolia. Journal of ethnopharmacology. 64 (3):195-210. DOI: https://doi.org/10.1016/S0378-8741(98)00133-0
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