IN VIVO ANTI-INFLAMMATORY ACTIVITY OF COMBRETUM BUCHIENSE LEAF METHANOL EXTRACT IN RATS (PAW OEDEMA MODELS)

Adeloye, D., Basquill, C., Aderemi, A. V., Thompson, J. Y., & Obi, F. A. (2019). Estimating the prevalence of noncommunicable diseases in Nigeria: A systematic review and meta-analysis. Journal of Global Health, 9(2), Article 020413. https://doi.org/10.7189/jogh.09.020413 DOI: https://doi.org/10.7189/jogh.09.020413

Ali, I. J., Adonu, C. C., Okorie, N. H., Okoye, N. N., &Okoye, F. B. (2023). Phytochemical analysis, antioxidant and antimicrobial activities of the leaves of Combretum buchiense Hutch & Dalziel (Combretaceae). South Asian Research Journal of Natural Products, 6(3), 248260.

Ali, I. J., Okorie, N. H., Ugodi, G. W., Ujam, T. N., Ugwu, C. O., Okwori, J. M., &Okoye, F. B. (2022). Phytochemical screening and antibacterial evaluation of extract and fractions of Combretum buchiense leaves. Journal of Pharmacognosy and Phytochemistry, 11(2), 285288.

Bekele, B., & Lemma, B. (2021). Bioactive compounds from ten species of the genus Combretum. International Journal of Chemical Sciences, 5(1), 1830.

Das, B. K., Al-Amin, M. M., Russel, S. M., Kabir, S., & Hannan, J. M. A. (2016). Analgesic and anti-inflammatory activities of the fruit extract of Ampelocissuslatifolia (Roxb) in laboratory animals. British Journal of Pharmaceutical Research, 4(12), 14771485. https://doi.org/10.9734/BJPR/2014/10876 DOI: https://doi.org/10.9734/BJPR/2014/8702

Ibeabuchi J. A, 1Ndidiamaka H. O, Gerald W. U, Nonye T. U, Chigozie P. O, Chibueze V. A & Raymond M O, (2023). Study of anti-ulcerogenic effect of methanol extract and fractions of the leaves of Ocimum gratissimum (lamiaceae), on ethanol-induced ulcer in rats fudma Journal of Sciences (FJS) Vol. 7 No. 6, , 214 - 220 DOI: https://doi.org/10.33003/fjs-2023-0706-2039

Kwatra, B. (2020). A review on potential properties and therapeutic applications of grape seed extract. World Journal of Pharmaceutical Research, 9(8), 25192540. https://doi.org/10.20959/wjpr20208-17747

Mohanraj, R., & Kumar, S. (2019). Anti-inflammatory potential of cardiac glycosides from Calotropisprocera in animal models. Journal of Ethnopharmacology, 241, Article 111965. https://doi.org/10.1016/j.jep.2019.111965 DOI: https://doi.org/10.1016/j.jep.2019.111965

Navarro, P., Giner, R. M., &Recio, M. C. (2017). Anti-inflammatory activity of saponins from various plant sources. Phytochemistry Reviews, 16(4), 573590. https://doi.org/10.1007/s11101-017-9504-3

Okorie, N H. Omorevbarhia. O, Umerie. S C, Aniefuna, E.I, Ujam, N T & Ali I J (2024) Proximate, Phytochemical, Mineral composition and Antioxidant effects of methanol Extract of Persea americana (Avzczdo peer seed) FUDMA Journal of Sciences (FJS) Vol. 8 No. 3,, 166 174 DOI: https://doi.org/10.33003/fjs-2024-0803-2303

OECD. (2018). Test No. 425: Acute oral toxicity: Up-and-down procedure. OECD Guidelines for the Testing of Chemicals, Section 4. https://doi.org/10.1787/9789264071049-en DOI: https://doi.org/10.1787/9789264071049-en

Ogunmola, O. J., Oladosu, Y., & Adebayo, A. O. (2021). Prevalence and determinants of chronic diseases among older adults in a rural community in Osun State, Nigeria. Journal of Aging Research, 2021, Article 6674198. https://doi.org/10.1155/2021/6674198

Ojo, O., Adebayo, O., &Olaleye, O. (2021). Atopic dermatitis in sub-Saharan Africa: A review of the epidemiology and management challenges. Dermatology Research and Practice, 2021, Article 5560950. https://doi.org/10.1155/2021/5560950

Pannu, A., Goyal, R. K., & Sharma, S. (2021). Emerging role of flavonoids in the treatment of depression. Biomolecules, 11(12), Article 1825. https://doi.org/10.3390/biom11121825 DOI: https://doi.org/10.3390/biom11121825

Salminen, A., Lehtonen, M., Suuronen, T., Kaarniranta, K., &Huuskonen, J. (2018). Terpenoids: Natural inhibitors of NF-B signaling with anti-inflammatory and anticancer potential. Cellular and Molecular Life Sciences, 65(19), 29792999. https://doi.org/10.1007/s00018-008-8103-5 DOI: https://doi.org/10.1007/s00018-008-8103-5

Serafini, M., Peluso, I., &Raguzzini, A. (2017). Flavonoids as anti-inflammatory agents. Proceedings of the Nutrition Society, 69(3), 273278. https://doi.org/10.1017/S002966511000162X DOI: https://doi.org/10.1017/S002966511000162X