PRODUCTION AND CHARACTERIZATION OF ANTI-DIABETIC GOLD NANOPARTICLES USING THE LEAF EXTRACT OF MANGIFERA INDICA
DOI:
https://doi.org/10.33003/fjs-2024-0806-2965Keywords:
Green nanotechnology, Mangifera indica extract, Green synthesis, EnzymesAbstract
Diabetes has continued to affect the well-being of millions of individuals all over the world. More than seventy percent of Africans have undiagnosed diabetes mellitus, with Nigeria among the list of the African countries recording most undiagnosed cases. Biologically synthesized gold nanoparticles using the extracts of plants have continued to gain grounds in the treatment of diabetes. In the present research, a straightforward green method was used to form gold nanoparticles (AuNPs) from Mangifera indica leaf extract. Transmission electron microscopy (TEM), dynamic light scattering (DLS), ultraviolet visible spectroscopy (UV-Vis), X-ray diffraction (XRD), and selected area electron diffraction (SAED) were used to characterize the nanoparticles. Using XRD and SAED, the AuNPs' crystallinity was ascertained. The TEM revealed particles of various morphologies, and the UV-Vis revealed a surface plasmon resonance (SPR) at 539 nm. The stability of the colloidal suspension was implied by the DLS measurement, which revealed a hydrodynamic size of 31.74 nm and a zeta potential of -23.7 mV. With percentage inhibitions that were about equivalent to that of acarbose, the conventional medication, the AuNPs demonstrated strong antidiabetic efficacy against the alpha-glucosidase and alpha-amylase enzymes. The research revealed the potential of Mangifera indica leaf extract-mediated gold nanoparticles in treatment of diabetes.
References
Anantatmula, V.S., (2015). Strategies for Enhancing Project Performance, Journal of management Engineering 31 (6), 401-501
Aaltonen, K., (2011). Project Stakeholder Analysis as an Environmental Interpretation Process. International Journal Project Management 29(2), 165183
American Institute of Architects, (2007). Integrated Project Delivery: A Guide.
Bernard, (2021). The Impact of a Call Centre on Communication in a Programmed and its Projects, International Journal of Project Management 31 (7), 1006–1016.
Brewer, G., Strahorn, S., (2012), Trust and the Project Management Body of Knowledge, Engineering Construction Architecture Management 19 (3), 286–305.
Bartleby, (2020), Construction Project: Complex and Unique Environment.
Retrieved from www.bartleby.com
Buckley, et al., (2009). Cultural Awareness in Knowledge Transfer to China – The Role of Guanxi and Mianzi. In: Foreign Direct Investment, China and the World Economy.
Berggreen, L., (2015). Project Management Communication 2.0 - The Sociotechnical Design of PM for Professional Communicators. In: IEEE International Professional Communication Conference, 2015-Septe
Campbell, G., (2011). The Complete Idiot's Guide to Project Management. Alpha Books, Indianapolis, IN.
Ceric, A., (2014). Minimizing Communication Risk in Construction: A Delphi Study of the Key Role of Project Managers. Journal of Civil Engineering Management 20 (6), 829–838.
Culo, K., Skendrovic, V., (2010). Communication Management Is Critical for Project Success. Informatologia 43 (3), 228–235.
Daim, T. et al., (2012). Exploring the Communication Breakdown in Global Virtual Teams.
International Journal of Project Management 30, 199–212.
Dreesen, T., et al., (2016). Beyond the Border: A Comparative Literature Review on Communication Practices for Agile Global Outsourced Software Development Projects. In: 2016 49th Hawaii, International Conference on System Sciences (HICSS), pp. 4932–4941.
Decker, E., (2015). Trust: The Foundation for Building Cohesive Teams, pp. 1–10.
Furnell, R., (201)4. Can social networking improve project management? An exploratory study of UK professional experience. In: International Conference on Information Society (i-Society 2014), pp. 152 – 156.
Guffy, M.E., (2007). Essential of Business Communication, Seventh ed. Thomson.
Hoezen, M. (2016). The Competitive Dialogue Procedure: Negotiations and Commitment in Inter-Organizational Construction Projects. Doctoral Dissertation, University of Twente, Enschede, Netherlands
Hakanen, M., and Soudunsaari, A., (2012). Building Trust in High-Performing Teams. Technology Innovation Management Review 2 (June), 38–41.
Hysa, B., and Spalek, S., (2019). Opportunities and Threats Presented by Social Media in Project Management. Heliyon 5 (4), 01488.
Hyginus E, (2020). Factors Causing Ineffective Communication and Its Effect on Construction Project.
International Journal of Engineering and Science 10(8), (2020), pp 19 - 26
Henderson, L., et al., (2004). The Centrality of Communication Norm Alignment, Role Clarity, and Trust in Global Project Teams. International Journal of Project Management.
Jonny F. (2024). 6 Types of Construction Key Differences. Pp 1 - 15
Kashiwagi, J. (2013). Dissertation. “Factors of Success in Performance Information Procurement System / Performance Information Risk Management System.” Delft University, Netherlands
Kelly, S., and MacDonald, P., (2019). A Look at Leadership Styles and Workplace Solidarity Communication. International Journal of Business Communication.
Kittler, M.G., (2011). Beyond Culture or Beyond Control? Reviewing the Use of Hall’s High-/Low-Context Concept. International Journal of Cross-Cultural Management 11, 63–82.
Lepatner, B.B. 2007, Broken Buildings, Busted Budgets, The University of Chicago Press, Chicago.
Liu, W.H., and Cross, J.A., (2016). A Comprehensive Model of Project Team Technical Performance. International Journal of Project Management 34 (7), 1150–1166.
Lee-Kelley, L., (2006). Locus of Control and Attitudes to Working in Virtual Teams. International Journal Project Management 24 (3), 234–243.
Livesey, P.V., (2016). Insights of Project Managers into the Problems in Project Management. Construction Economic of Building 16 (1), 90–103.
Mavuso, N.M., and Agumba, J.N., (2016). Factors of Communication Management for Successful Project Delivery in the Swaziland Construction Industry, pp. 19–21.
Muszynska, K., (2018). Communication Maturity Model for Organizations Realizing EU Projects. Procedia Computer Science 126, 2184–2193.
Mesly, O., (2015). Exploratory Findings on the Influence of Physical Distance on Six Competencies. International journal of project Management 33 (7), 1425–1437.
Meyer, E., (2015). The Culture Map. Public Affairs, New York.
Morris, P., (2008). The Basics Business Communication. (3rd (Third). Thomson South-Western
Mavuso, N.M., Agumba, J.N., (2016). Factors of Communication Management for Successful Project Delivery in the Swaziland Construction Industry, pp. 19–21.
Manoj Ray, D., Samuel, P., (2016). Improving the Productivity in Global Software Development. Advance Intelligent System Computing 424, 175–185.
Mahamid, I., (2016). Micro and Macro Level of Dispute Causes in Residential Building Projects: Studies of Saudi Arabia. Journal of King Saud University Engineering Science 28 (1), 12–20.
Meid, A. (2015). An Engineering Management Analysis of Communication System in an Organization that Supplies the Mining Industry. https://ujdigispace.uj.ac.za/bitstream/handle
Oyegoke, et al., (2013). Stakeholders Assessment of Constraints to project delivery in the Nigerian. Construction Industry. International Journal of Build Environment and Sustainability. 4(1), 2017, Pp.2
Pant, I., (2008). Project Management Education: The Human Skills Imperative. International Journal of Project Management 26 (2), 124–128.
Pheng, L.S., (2018). Project Communications Management.
PMI, 2017. A Guide to the Project Management Body of Knowledge (PMBOK Guide), sixth ed. Project Management Institute. A Guide to the Project Management Body of Knowledge (PMBOK Guide).
Pivec, M., (2019). Employment Background Influence on Social Media Usage in the Field of European Project Management and Communication. Journal of Business Research 94, 280–289.
PricewaterhouseCoopers, (2009). “Need to know: Delivering capital project value in the downturn.” https://www.pwc.com/co/es/energia-mineria-y-servicios-publicos/assets/need-to-know-eum-capital-projects.pdf . Accessed September 16, 2015.
Pullin, P., (2010). Small Talk, Repport, and International Communicative Competence: Lessons to Learn from belf. Journal of Business Communication 47 (4), 455–476.
Roudias, J., (2015). Mastering Principles and Practices in PMBOK, Prince 2, and Scrum: Using Essental Project Management Methods to Deliver Effective and Efficient Projects. Paul Boger.
Reed, A.H., Knight, L.V., (2013). Exploring the Role of Communication Media in the Informing Science Model: An information technology project management perspective. Information Science 16 (1), 131–145.
Rai, U., and Rai, S.M., (2014). Effective Communication (Sixth). Himalaya Publishing House.
Senaratne, S., (2016). Communication in Construction: A Management Perspective through Case Studies in Sri Lanka. Architect. Engineering Design Management 12 (1), 3–18.
Salman et al., (2014), Jaser, (2005), Flanagan and Norman, 1993; Smith, (2006) and Zou et al., (2005). Mapping the Risk Response Strategies on Classified Building Construction-Related Risks
FUDMA Journal of Sciences (FJS) Vol. 6 No. 6, December, 2022, pp 125-137
Sluyts, K. et al., (2011). Building Capabilities to Manage Strategic Alliances. Industrial Marketing Management 40 (6), 875–886.
Steyn, H., (2012). Project Management a Multi-Disciplinary Approach (3rd Revise). FPM Publishing, Pretoria, 2012.
Van der Walt, A., et al., (2016). Marketing Management. 3rd ed. Kenwyn: Juta.
Wikipedia (2020). Effective Communication and Communication Channel.
http://en.wikipedia.org/wiki/ Communication management
Wikipedia, (2015), Influence of Communication Problems on Project Performance in Nigeria
African Journal of Engineering Research 7(3), 2-5
Warner-Søderholm, G., 2013. Beyond A Literature Review of Hall’s Context Dimension: Scale Development, Validation & Empirical Findings within a Norwegian Study. International Journal of Business Management 8 (10)
Yang, R.J., and Wang, Y., (2014). Stakeholders’ Attributes, Behaviors, and Decision-making Strategies in Construction Projects: Importance and Correlations in Practice. Project Management Journal 45 (3), 74–90.
Yun, S. (2013). The impact of the business-project interface on capital project performance. The University of Texas at Austin. Retrieved from http://repositories.lib.utexas.edu/handle/2152/22 804
Zulch, B. G. (2014). Communication: The Foundation of Project Management. Conference on Enterprise Information System
Published
How to Cite
Issue
Section
FUDMA Journal of Sciences
