ETHNOBOTANICAL SURVEY OF MEDICINAL PLANTS USED IN THE TREATMENT OF CANCER IN DUTSIN-MA LOCAL GOVERNMENT AREA OF KATSINA STATE, NIGERIA
Abstract
Ethnopharmacological surveys showed that herbal remedies and their products are mostly preferred type of alternative and complementary medicine (ACM) globally. In Dutsin-Ma Local Government Area (LGA) like other places herbal remedies are popularly employed against many ailment including tumor and cancer. Therefore, this study aimed to report and document the ethnobotanical survey of the plants used in the management of tumor and cancer in Dutsin-Ma Local Government Area of Katsina State, Nigeria. Traditional medicine practitioners (TMPs) living within the area of study were cross-examined by employing questionnaires forms and key informant survey. Forty-two (42) different plant species were discovered to be employed against cancer and tumor management. The results obtained showed the parts of plant used for the herbs include; roots (4), bark (10), whole plant (13), seeds (5), fruits (3), stem (1) and leaves (6). The plant families Leguminosae caesalpinoideae and Leguminosae mimosoideae appeared more in the ethno-surveyed plant list though other families are involved. Many of these plants are mix together as storehouses for active compounds which may be good template for cancer and tumor management. The preparation of the remedies include; grinding to powder form then dispersing in either water or milk for drinking, or either mix with shear butter or water and administered on the affected part of the body. The reports showed that the herbal remedies indentified are effective for the treatment of cancer in Dutsin-Ma local government area. Hence, it is imperative for ethnobotanists and chemists to establish the toxicity and efficacy of these
References
Adesina S. K. (2008). Traditional medicine care in Nigeria. Today Newspaper: Wednesday, 23, April 2008.
Ampitan T. A. (2013). Ethnobotanical survey of medicinal plants in Biu local government area of Borno state, Nigeria. Comprehensive Journal of Herbs and Medicinal Plants, 2(1): 7 – 11.
Mbaveng A. T., Damen F., Mpetga J. D. S., Awouafack M. D., Tane P., Kuete V. and Efferth T. (2019). Cytotoxicity of Crude Extract and Isolated Constituents of the Dichrostachys cinerea Bark towards Multifactorial Drug-Resistant Cancer Cells. Evidence-Based Complementary and Alternative Medicine. Article ID 8450158 ://doi.org/10.1155/2019/8450158.
Burkill H. M. (1995). The useful plants of West Tropical Africa. 2nd ed. Vol. 3. Families J-L. Royal Botanic Gardens, Kew. Pp. 857.
Deeni Y.Y. and Sadiq N. M. (2002). Antimicrobial properties and phytochemical constituents of the leaves of African mistletoe (Tapinanthus dodoneifolius (DC) Danser) (Loranthaceae): an ethnomedicinal plant of Hausaland, Northern Nigeria. J. Ethnopharmacol. 83:235-240.
Eisenberg D, Davis R. and Ettner S (1998). Trends in alternative medicine use in the United States 1990-1997; results of a follow up survey. Journal of American Medical Association, 280: 1569-1575.
Tatematsu H., Mom M., Yang T-H., Chang J-J., Lee T. T-Y and Lee K-H (1991). Cytotoxic Principles of Securinega virosa: Virosecurinine and Viroallosecurinine and Related Derivatives. Journal of Pharmaceutical Sciences, 80(4): 325-328
Independent News (2017). The Alarming Rate of Cancer Deaths in Nigeria. Published on March 13, 2017. Retrieved from http://www.The Alarming Rate of Cancer Deaths in Nigeria _ Independent Newspapers Limited March 22, 2017.html
Kumar R. S., Rajkapoor B. and Perumal P. (2011). In vitro and in vivo anticancer activity of Indigofera cassioides Rottl. Ex. DC. Asian Pac J Trop Med., 4:379-385.
Ochwang’i, D.O., Charles N. Kimwele, Jemimah A. Oduma, Peter K. Gathumbi, James M. Mbaria, Stephen G. K. (2013). Medicinal plants used in treatment and management of cancer in Kakamega County, Kenya. Journal of Ethnopharmacology, http://dx.doi.org/10.1016/j.jep.2013.11.051i
Ojewole J. A. O. (2004). Evaluation of the analgesic, anti-inflammatory and antidiabetic properties of Sclerocarya birrea (A. Rich.) Hochst. Stem bark aqueous extract in mice and rats. Phytotherapy Research, 18: 601-608.
Olapade E. O (2002). The herbs for good health: the 50th Anniversary Lecture of the University of Ibadan. NARL Specialist Clinic, Ibadan, Nigeria. Pp. 230.
Rayanil K. O., Bunchornmaspan P. and Tuntiwachwuttikul P. (2011). A new phenolic compound with anticancer activity from the wood of Millettia leucantha. Arch Pharm Res., 34:881-886.
Ngulde S. I., Sandabe U. K., Abounader R., Dawson T. K., Zhang Y., Iliya I. and Hussaini I. M. (2019). Ethanol Extract of Securidaca longipedunculata InducesApoptosis in Brain Tumor (U87) Cells. BioMed Research International, Article ID 9826590, https://doi.org/10.1155/2019/982659
Salem M. M., Davidorf F. H. and Abdel-Rahman M. H. (2011). In vitro anti-uveal melanoma activity of phenolic compounds from the Egyptian medicinal plant Acacia nilotica. Fitoterapia 82:1279-1284.
Soladoye M. O., Amusa N. A, Raji-Esan S. O., Chukwuma E. C. and Taiwo, A. A. (2010). Ethnobotanical Survey of Anti-Cancer Plants in Ogun State, Nigeria. Annals of Biological Research, 1(4): 261-273.
Traore R (2000). Etude pharmacologique chez l’animal de l’extrait aqueux de Tapinanthus dodoneifolius (DC). Danser (Loranthaceae) utilisée en tradithérapieanti-asthmatique au Burkina Faso. Thèse de pharmacie. FSS. Université d’Ouagadougou, Burkina Faso.
WHO (2018). Cancer Key facts published on 12 September 2018. Retrieved from http://www.who.int/news-room/fact-sheets/detail/cancer on 22 September, 2018.
WHO (2003). World Health Organization. Traditional medicine 〈http://www.who.int/mediacentre/factsheets/fs134/en/print.html〉(revised 2008).
WHO (2010). “Cancerâ€âŒ©http://www.who.int/mediacentre/factsheets/fs297/en/〉 (Retrieved 2011-01-05)
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