SYNTHESIS, CHARACTERIZATION, CYTOTOXICITY AND ANTIMICROBIAL STUDIES OF SCHIFF BASE DERIVED FROM 2-BENZOYLBENZOIC ACID AND 4-NITRO ANILINE AND ITS METAL(II) COMPLEXES
DOI:
https://doi.org/10.33003/fjs-2023-0706-2104Keywords:
Schiff base, 2-benzoylbenzoic acid, 4-nitro aniline, Metal complexes, Antimicrobial activity, Solubility, Cytotoxicity activityAbstract
Schiff base derived from 4-nitro aniline and 2-benzoylbenzoic acid, and its Mn(II), Co(II) and Ni(II) complexes have been synthesized and characterized based on their melting/decomposition temperature, solubility, magnetic and infrared analysis. Gravimetric analysis and Job’s method of continuous variation reveal that all metal complexes are in 1:2 metal-ligand ratios. All complexes have low conductance value (13.6-20.6 ohm-1cm-1mol-1), indicating that they are non-electrolyte. However the cytotoxic analysis indicates that Co(II) complex was more toxic with the LC50 value of 181.72 ug/ml than the other complexes. The Schiff base and its respective metal complexes were screened for their antimicrobial activities and the results revealed that the compounds showed significant activity against all isolates.
References
Agbo, S. N., & Oparaku, O.U., (2006). Positive and Future Prospects of Solar Water Heating in Nigeria. The Pacific Journal of Science and Technology 7, 191-198.
Akinoso, R., & Aremu, A. K. (2013). Potential use of box type solar cooker in developing countries. The Journal of the Association of Professional Engineers of Trinidad and Tobago, 41(1), 11-17
Asif, M., & Muneer, T., (2013). Thermal Energy: Solar Technologies. In Encyclopedia of Environmental Management. Taylor and Francis New York, 2498-2507.
Bamisile, O., Dagbasi, M., Babatunde, A., & Ayodele O., (2017). A Review of Renewable Energy Potential in Nigeria; Solar Power Development Over the Years. Engineering and Applied Science Research 44, 242-248.
BIS Standard (1993), Bureau of Indian Standard, Solar energy-calibration of field pyranometers by comparison to a reference pyranometers.. Indian pp 1-2.
Fernandes, L., Fernandes, J. R., & Tavares, P. B. (2022, November). Design of a Friendly Solar Food Dryer for Domestic Over-Production. In Solar (Vol. 2, No. 4, pp. 495-508). MDPI.
Funk, P.A. (2002). ASAE Standard: ASAE X580 (SE-414 revised Voting Draft). Testing and Reporting Solar Cooker Performance, 1-7.
Garba, M. M. (2009). Thermal energy materials and systems optimisation for solar drying and cooking. October.
Karekezi, S., Kithyoma, W., & Afrepren. (2003). Renewable Energy in Africa: Prospects and Limits. The Workshop for African Energy Experts on Operationalizing the NEPAD Energy Initiative 2-4, 1-27.
Kelechi, I. G., Zungeru, A. W., Ayobami, O. E., Habib, H., & Olugbenga, A. F. (2014). Design and Modelling of a Solar Water Heating System. Industrial Engineering Letters 4, 70-79.
Kronhardta, V., Alexopoulos, S., Reißel, M., Sattler, J., Hoffschmidt, B., Hänel, M. & Doerbeck, T., (2014). High-Temperature Thermal Storage System for Solar Tower Power Plants with Open-Volumetric Air Receiver Simulation and Energy Balancing of a Discretized Model, 870-877.
Mullick S.C, Kandpal T.C, Kumar S (1996).Testing of box-type solar cooker second Figure of merit F2 and its variation with load and number of pots. Solar energy 57 (5) pp 409- 413.
Newsom, C., & Stakeholder Democracy Network (SDN). (2012). Renewable Energy Potential in Nigeria: Low-carbon Approaches to Tackling Nigeria’s Energy Poverty. International Institute for Environment and Development (IIED). The SUNGAS Project, 1-33.
Osueke, C. O. & Ezugwu, C. A. K., (2011). Study of Nigeria Energy Resources and Its Consumption. International Journal of Scientific and Engineering Research 2, 1-8.
Rapu, C. S., Adenuga, A. O., Kanya, W. J., Abeng, M. O., Golit, P. D., Hilili, M. J., Uba, I. A., & Ochu, E. R. (2015). Analysis of Energy Market Conditions in Nigeria. Central Bank of Nigeria, Occasional Paper, 1-72.
Sambo, A. S. (2009). Strategic Developments in Renewable Energy in Nigeria. International Association for Energy Economics, Third Quarter, 15-19.
Solar Resource Map, (2017). Direct Normal Irradiation-Nigeria. World Bank Group.
Tesfay, M. & Venkatesan, M., (2013). Simulation of Thermocline Thermal Energy Storage System using C. International Journal of Innovation and Applied Studies 3, 354-364.
Published
How to Cite
Issue
Section
FUDMA Journal of Sciences
