ISOLATION OF SITOSTEROL AND STIGMASTEROL FROM THE ROOTS OF CROTON PENDULIFLORUS
DOI:
https://doi.org/10.33003/fjs-2023-0706-2097Keywords:
Croton Penduliflorus, Stigmasterol, Sitosterol, Nuclear Magnetic ResonanceAbstract
The primary aim of this study was to isolate Sitosterol from the root of Croton Penduliflorus. Croton Penduliflorus Hutch (Euphorbiaceae) commonly known as Turk’s Cap though to originate from Malaysia, is a tropical evergreen plant widely distributed in the southern part of Nigeria. It is employed in folklore medicine both as drastic and fugitive, as well as a psychotropic medicinal plant. It is also credited with antimicrobial, antivenom, antiparalytical, rubefacient and anti-tumor potencies Extraction of the roots of Croton Penduliflorus with ethanol and partitioning of the extract with hexane, chloroform and ethyl acetate followed by column chromatography of the chloroform extract has led to the isolation of sitosterol, stigmasterol and a substituted benzene derivative. Their structures were established using 1D and 2D NMR, LCMS, and FTIR spectral analysis and a comparison of their spectral data with literature reports.
References
Auchincloss, A. H., Diez Roux, A. V., Dvonch, T., Brown, P. L., Bar, G. R., Daviglus, M. L., . . . O'Neill, M. S. (2008). Associations between Recent Exposure to Ambient Fine Particulate Matter and Blood Pressure in the Multi-Ethnic Study of Atherosclerosis. Environmental Health Perspectives , 116(4).
Cao, S., Qian, G., Xue, T., Wang, B., Wang, L., Duan, X., & Zhang, J. (2021). Long-term exposure to ambient PM2.5 increase obesity risk in Chinese adults: A cross-sectional study based on nationwide survey in China. Science of The Environment, 778, 145812. doi:doi.org/10.1016/j.scitotenv.2021.145812
Eze, I. C., Schaffner, E., Fischer, E., Schikowski, T., Adam, M., Imboden, M., . . . Nicole, P. (2014). Long-term air pollution exposure and diabeties in a population-based Swiss cohort. Environment Internaional, 70, 95-105. doi:doi.org/10.1016/j.envint.2014.05.014
Hammed, L. A., & Muhammed, M. I. (2022). Atmospheric Physics; Air Pollution and Analysis Using Purple Air Data. African Scientific Report. doi:10.46481/asr/2022.1.2.42
Hernandez, G., Berry, T.-A., Wallis, S. L., & Poyner, D. (2017). Temperature and Humidity Effects on Particulate Matter Concentrations in a Sub-Tropical Climate During Winter. International Proceedings of Chemical, Biological and Environmental Engineering, 102. doi:10.7763/ipcbee.2017.v102.8
Kan, H., Chen, R., & Tong, S. (2012). Ambient air pollution, climate change and population health in China. nvironment Int, 42, 10-19. doi:10.1016/j.envint.2011.03.003
Kim, M. J. (2019). Changes in the Relationship between Particulate Matter and Surface Temperature in Seoul from 2002-2017. Atmosphere, 10, 238. doi:doi.org/10.3390/atmos10050238
Liu, F., Tan, Q.-W., Jiang, X. x., Jiang, W.-J., & Song, D.-L. (2017). Effect of Relative Humidity on Particulate Matter Concentration and Visibility During Winter in Chengdu. Environmental Science, 39(4), 1466-1472. doi:10.13227/j.hjkx.201707112
Loannis, m., Elisavet, S., Agathangelos, S., & Eugenia, e. (2020). Environmental and Health Impacts of Air Pollution: A Review. Front. Public Health. doi:doi.org/10.3389/fpubh.2020.00014
Nam, E., Kishan, S., Baldauf, R. W., Fulper, C. R., Michael, S., & Warila, J. (2010). Temperature Effects on Particulate Matter Emissions from Light-Duty, Gasoline-Powered Motor Vehicles. Environmental Science & Technology, 44(12), 4672-4677. doi:https://doi.org/10.1021/es100219q
Zhang, L., Cheng, Y., Zhang, Y., He, Y., Gu, Z., & Yu, C. (2017). Impact of Air Humidity Fluctuation on the Rise of PM Mass Concentration on the High-resolution Monitoring Data. Aerosol and Air Quality Research, 17, 543-552. doi:10.4209/aaqr.2016.07.0296
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