PHYTOCHEMICAL AND ANTIHELMINTIC STUDIES OF THE LEAVES EXTRACT OF SIDA ACUTA BURM. F AGAINST TAENIA saginata

Abstract

Sida acuta is considered as an agricultural weed, but it is a valuable plant in the traditional medicines of Asia and Nigeria. In the traditional medicine of India and Nigeria, the leaves and roots are used as a remedy for bacterial, fungal, intestinal helminth infections, dandruff, rheumatism, liver problems, kidney stones, nervous disorders, testicular swelling and elephantitis. The study was carried out to evaluate the phytochemical and antihelmintic studies of the leaves extract of sida acuta burm. f against taenia saginata. The methanol, acetyl acetate and n-hexane extracts were subjected to preliminary Phytochemical screening for the identification of different Phytoconstituents and was found to have alkaloids, steriods, flavonoids, glycosides, cardiac glycosides, saponins, tannins and anthraquinones. The different concentrations of methanolic, acetyl acetate and n-hexane extracts were subjected to anthelminthic study and the results were compared with that of standard drug Albendazole. Different concentrations of leaf extracts were tested to evaluate Anthelmintic activity using Sida acuta. Both the extracts were found to possess vermicidal activity with the methanolic extract showing higher efficacy compared to ethyl acetate and n-hexane extracts and the results were compared with standard drug Albendazole.