PHYTOCHEMICAL AND ANTIHELMINTIC STUDIES OF THE LEAVES EXTRACT OF SIDA ACUTA BURM. F AGAINST TAENIA saginata

  • Hassan Usman
  • Ismail Abdulkarim
Keywords: Phytochemical Screening, Sida acuta, Anthelmintic activity, Albendazole

Abstract

Sida acuta is considered as an agricultural weed, but it is a valuable plant in the traditional medicines of Asia and Nigeria. In the traditional medicine of India and Nigeria, the leaves and roots are used as a remedy for bacterial, fungal, intestinal helminth infections, dandruff, rheumatism, liver problems, kidney stones, nervous disorders, testicular swelling and elephantitis. The study was carried out to evaluate the phytochemical and antihelmintic studies of the leaves extract of sida acuta burm. f against taenia saginata. The methanol, acetyl acetate and n-hexane extracts were subjected to preliminary Phytochemical screening for the identification of different Phytoconstituents and was found to have alkaloids, steriods, flavonoids, glycosides, cardiac glycosides, saponins, tannins and anthraquinones. The different concentrations of methanolic, acetyl acetate and n-hexane extracts were subjected to anthelminthic study and the results were compared with that of standard drug Albendazole. Different concentrations of leaf extracts were tested to evaluate Anthelmintic activity using Sida acuta. Both the extracts were found to possess vermicidal activity with the methanolic extract showing higher efficacy compared to ethyl acetate and n-hexane extracts and the results were compared with standard drug Albendazole.

References

Abe, R. T. (2013). Extraction and isolation of flavonoids present in the methanolic extract of leaves of acanthosperm hispidiumDC. Global journal of medicinal plant research. Vol.1, pp. 111-123.

Chinelo A. Ezeabara1, Miracle O. Egenti (2018) Phytochemical and antimicrobial investigations on various parts of Sida acuta Burm. f. Journal of Ayurvedic and Herbal Medicine 2018; 4(2): 71-7. ISSN: 2454-5023 J. Ayu. Herb. Med.

Dewanjee, S., Maiti, A., Kundu, M. and Mandal, S.C. (2007). Journal of Pharmaceutical Science, 6(2), 121-123.

Ghosh T, Maity T.K, Bose A, and Dash G.K (2005). Indian journal of natural products, , 21,p 16-19.

Joseph, O.O. and Adeyemi, A.P. Medical Practice and Reviews, (2011), 2 (2), pp 23 – 28.

Majori, M.C. Clinical Microbiology Reviews, 1999, 12 (4): 564 – 582.

Odewade J.O and Odewade L.O (2023) Evaluation of antibacterial and antioxidant properties of leaf extract of Chrysophylum albidum against selected bacterial pathogens. Fudma Journal of Science (FJS) Vol. 7. No. 2. Pp131-140. ISSN 2616-1370. DOI hhts://doi.org/10.33003/fjs-2023-0702-1721

Oyewale, A.O.; Audu, O.T. Amupitan, J.O. (2004). Journal of Chemical Society of Nigeria, 4: 162 -165.

Palaksha, M.B and K. Ravishankar (2012). Phytochemical Screening and Evaluation of in vitro Antibacterial and Antihelminthic Activities of S. acuta Leaf Extracts, Journal of Chemistry, 4(11), 4757 – 4761.

Salihu L. and Ado K. (2013). Phytochemical and antimicrobial screening of constituents of some medicinal plants. Asian Journal of Plant Science and Research, 2013, 3(4):1-7. ISSN : 2249-7412

Salihu, L. and Garba, S. Biological and Environmental Science Journal for the Tropics, 2008, 5 (1): 164 – 168.

Senthilkumar R.P, V. Bhuvaneshwari, V.Malayaman, R. Ranjithkumar1 and S. Sathiyavimal (2018). Phytochemical Screening of Aqueous Leaf Extract of Sida acuta Burm. F. and its Antibacterial Activity. Journal of Emerging Technologies and Innovative Research (JETIR) www.jetir.org. Volume 5, Issue 8. ISSN-2349-5162.

Sofowora, A (1993). Medicinal Plants and Traditional Medicines in Africa. Spectrum Books Ltd., Sunshine House, Ibadan, Nigeria, pp 150 – 153.

Verma, S (2016). A review study on phytochemical and pharmacological properties of Ficus benghalensis (Indian Banyan tree). International Journal of Science, Engineering and Technology. 2 (4): 73-75

Published
2023-04-30
How to Cite
Usman H., & Abdulkarim I. (2023). PHYTOCHEMICAL AND ANTIHELMINTIC STUDIES OF THE LEAVES EXTRACT OF SIDA ACUTA BURM. F AGAINST TAENIA saginata. FUDMA JOURNAL OF SCIENCES, 7(2), 223 - 226. https://doi.org/10.33003/fjs-2023-0702-1736