DETECTION OF SALMONELLA SPECIES AMONG PATIENTS WITH SUSPECTED CASES OF TYPHOID FEVER IN WUDIL GENERAL HOSPITAL

  • M. M. Ahmad
  • U. Z. Umar
  • I. I. Abdullahi
  • I. H. Mukhtar
  • S. Isa
Keywords: Salmonella typhi, Typhoid fever, Detection, Patient

Abstract

The prevalence of Salmonella typhi infection among patients with reported cases of typhoid fever in Wudil general hospital was investigated by serological examination of blood samples and by culture method of stool collected from patients attending the Hospital. A total of 140 each of blood and stool samples were analyzed using the method of Widal slide agglutination test and selective cultivation on Salmonella-Shigella (SS) agar respectively. Out of this, 112 (80%) of the samples were found to be positive, while 28 (20%) of the samples were found to be negative for both Widal agglutination test and culture on SS agar. In the study, males were more infected by S. typhi than females. The presence of these organisms among patients with symptoms of typhoid fever is a threat to public health especially if immunocompromised patients are involved. Based on the research findings it can be seen that substantial numbers of reported patients were exposed to predisposing factors for typhoid fever infection. Hence it is recommended that action should be expedited in the provision of safe drinking water to the public; discourage defecation in an open area and the improvement of personal hygiene

References

Adams, M. R. Moss, M.O. (2007). Food Microbiology; Royal Society of chemistry: Cambridge. Agarwal. K. Control of Communicable Diseases Manual (CCDM) 19th edition.

Adeleke, O.E., Adepoju, T.J. and Ojo, D.A. (2006). Prevalence of typhoid fever and antibiotic Susceptibility pattern of its causative agent Salmonella typhi. Nigerian J. Microbiol., 20(3): 1191-1197.

Agwu, E., Ihongbe, J.C, Okogun, G.R.,Inyang, N.J. (2009). High incidence of co-infection with malaria and typhoid in febrile HIV infected and AIDS patients in Ekpoma, Edo state, Nigeria. Brazilian Journal of Microbiology, 40, 329- 332.

Ajayi, O.E., Olukunle, O.F.,Boboye, B.E. (2015). Prevalence of Typhoid Fever among Different Socio-demographic Groups in Ondo State, Nigeria. Journal of Applied Life Sciences International, 3(2), 89-95.

Carol, A.,. Joseph, O.A., Palmer,R.S.(2009). Outbreak of Salmonella infection in hospitals in England and Wales. Br. Med. J., 289: 1161-1164.

Chin, J. (2016). Control of communicable disease manual. American Public Health Association, 17th edition, New York.

Crump, J.A.,Mintz, E.D. (2010). Global Trends in Typhoid and Paratyphoid Fever. Clinical Infectious Diseases, 50(2), 241-246.

Dimitrov T., Udo, E.E., Albaksami, O., Shehab, S.A., Kilani, A., Shehab, M. and Nakkas, A. (2007): Clinical and Microbiological Investigations of typhoid fever in an infectious disease hospital in Kuwait, Asian Medical Journal, 59(24): 851-854.

Hoffman, S.L., Flanigan,T.P.,Klancke,D.Leksana,B.,Rockhill, R.C., Narain, H.P., Pulungsih, S.Sutomo, A. and Moechtra, M.A. (2006). The Widal agglutination test, a valuable rapid diagnostic test in typhoid fever patients at the infectious disease hospital in Jakarta. American Journal Epidemiology, 123: 869-875.

Humphrey, T. (2004). Salmonella, stress responses and food safety. Nature Reviews Microbiology, 2, 504-509.

Ibekwe, A.C., I.O.,Okonko, A.U.,Onunkwo, E., Donbraye, E.T., Babalola, B.A. and Onoja, T.(2008). Baseline Salmonella agglutinin titres in apparently healthy freshmen in Awka, South Eastern, Nigeria. Science Research Essay, 3(9): 225-230.

Isa, S., Mahyudin, N. A., Sahil, S. M., Radu, S., Mahmud, N. K., and Rashid, A. (2019). Multiple Drug Resistance Among Staphylococcus aureus Strains Isolated from Cutting Boards of Commercial Food Premises: A Threat to Food and Public Health Safety. Journal of Biochemistry, Microbiology and Biotechnology, 7(1), 48-51.

Jegathesan, M., (1984).Salmonella serotype isolated from man in Malaysia over the 10 years period. Journal of Hygiene, Cambodia, 92: 395-399.

Kabiru, O. A.,Akeeb, O. B.,Wasiu, B.,Mutiu, B., Abiodun, E., Sunday, A.,Samuel O. A. and Stephen K. O.(2018). Tyhoid fever: tracking trend in Nigeria. American Journal of Tropical Medicine and Hygiene, 99(3):1-7.

Kabiru, O.A., Yetunde, O.O., Oladeji, G.O. and Akitoye, O.C. (2012). A retrospective study of community acquired Salmonella infections in patients attending public hospitals in Lagos, Nigeria. Journal of Infection in Developing Countries, 5(6), 387-395.

Marks, F., Von Kalckreuth, V. and Aaby, P. (2017). Incidence of invasive Salmonella disease in sub-Saharan Africa: a multicentre population-based surveillance study. Lancet, 5(3).

Mohammed, I., Chikwem, J.O. and Gashau, A.(2002). Determination by Widal agglutination of baseline titre for the diagnosis of typhoid fever in two Nigerian states. Scandinavian Journal Immunology,11(suppl): 153-156.

NPC/National Bureau of Statistics (2006). Availableat https://www.citypopulation.de/php/nigeria-admin.php?adm2id=NGA020044

Okonko, I.O., Soleye, F.A., Eyarefe, O.D., Amuson, T.A., Abubakar, M.J., Adeyi, A.O., Ojezele, M.O. and Fadeyi, A. (2010). Prevalence of Salmonella typhi among patients in Abeokuta South-WesternNigeria. British Journal of Pharmacology and Toxicology, 1(1), 6-14.

Published
2023-04-11
How to Cite
AhmadM. M., UmarU. Z., AbdullahiI. I., MukhtarI. H., & IsaS. (2023). DETECTION OF SALMONELLA SPECIES AMONG PATIENTS WITH SUSPECTED CASES OF TYPHOID FEVER IN WUDIL GENERAL HOSPITAL. FUDMA JOURNAL OF SCIENCES, 3(3), 535 - 539. Retrieved from https://fjs.fudutsinma.edu.ng/index.php/fjs/article/view/1600