RENIN-INHIBITORY BIOACTIVE PEPTIDES WITH ANTIHYPERTENSIVE PROPERTY: A REVIEW
DOI:
https://doi.org/10.33003/fjs-2020-0402-140Keywords:
Key words: Hypertension; Bioactive peptides; Renin inhibition; Mechanism of action.Abstract
Blood pressure is regulated by the renin angiotensin aldosterone system (RAAS). Renin-catalyzed conversion of angiotensinogen to angiotensin I is the rate-limiting step of the RAAS pathway, which arguably makes renin a better target for prevention, treatment and management of hypertension than Angiotensin-Converting Enzyme (ACE). Hydrolysis of food proteins releases bioactive peptides that can interact with receptors, enzymes and molecules in the organism to promote health. Several studies have shown that these bioactive peptides could be exploited for management of hypertension which is a major risk factor for cardiovascular diseases (CVDs). Antihypertensive peptides are bioactive peptides derived from plant and animal sources with inherent potential to ameliorate hypertension by different mechanism including scavenging of free radicals, reduced cholesterol level, inhibit angiotensin-converting enzyme (ACE) activity and renin production. Although there was sufficient information on ACE-inhibitory and antioxidative peptides while information on the potential role of renin-inhibitory peptides against hypertension is limited. Thus, herein the present review primarily used ISI, SCOPUS and PubMed indexed journals containing experimental reports to elucidate the potential role of bioactive peptides against antihypertensive effect via renin inhibition.
Key words: Hypertension; Bioactive peptides; Renin inhibition; Mechanism of action.
References
Aderolu, A.Z., Iyayi, E.A., and Onilude, A.A (2007). Changes in nutritional value of rice husk during Trichoderma viride degradation. Bulg. J.Agric, Sci., 13: 583-589.
Aderolu A.Z and Oyedokun G. T. (2008).Comparative utilization of biodegraded Rice Husk in the diets of Clarias gariepinus. Journal of fisheries and Aquatic Science 3 (5): 312-319
Agbabiaka, L. A. (2010) Aquaculture and pond management in the tropics. Vintage books limited, Owerri. Pp. 111.
Agbabiaka, L. A (2013). Evaluation of some under utilized protein feedstuff in diets of Clarias garienpinus fingerlings. International Journal of Tropic Agric and Food System, 4 (1): 10-12.
AOAC, (1990).Official Methods of Analysis.4th Edition, Association of Official Analytical Chemists, Washington DC.
Auta, J., Yashim, Y. E., Dambo, A. and Tiamiyu, B. B. (2013).Growth responses of African
Catfish, Clarias gariepinus, Fingerlings to imported and local feeds.International Journal of Applied Biological Research.5(1):55-61.
Belewu, M.A and Okhawere, O.C. (2008). Evaluation of feeding value of fungi treated rice husk to ram. Proceedings of the 25th Annual Conference of Nigeria society of animal production. Pp. 320 – 321.
Bene, C. and Heck, S (2005).Fish and food security in Africa.Naga, Worldfish center Quarterly, 28(3-4), pp .8-13.
Boyd Claude, E. (1982). Water quality management for pond fish culture.Elsevier science publishers, Neitherland. Pp:318.
Chapman, D and Kimstach, V. (1992). Selection of water quality variables.In:Water assessment . UNESCO, WHO and UNEP.59-126.
Chiokwe. G.I and Solomon, J,R. (2017). Growth respond and nutrient utilization of Clarias gariepinus fed bean cake. Journal of Bioscience and Biotechnology discovery. 2: 49-62.
Dan-kishiya, A. S. and Chiaha, Q. N. (2012).Physico-chemical parameters of some selected stations in Lower Usuma Reservoir, Bwari, Nigeria. Report and Opinion 4(2):1-6.
Dan-kishiya, A.S., Oboh, A. and Ibrahim, U.B. (2013).The prevalence of helminthes parasites in the gastrointestinal tract of wild African sharptooth catfish, Clarias gariepinus in Gwagwalada, Nigeria.Research journal of Costa Rican Distance Education University.(ISSN 1659-4266).5 (1).
Dan-kishiya A.S., Idowu, R.T and Onu, A.M (2017). Gradual replacement of Maize with kunnu waste in the diet for African sharptooth catfish fingerlings, Clarias gariepinus. Journal of recent trends in Natural sciences research and development.3: 1-6.
Food and Agriculture Organization of United Nations (FAO). (2009). The State of World Fisheries and Aquaculture 2008. Rome: FAO Fisheries and Aquaculture Department.
Iyayi , E.A and Aderolu, A.Z. (2004). Enhancement of feeding value of some agro-industrial by-products for laying hens after their solid state fermentation with Trichoderma virridii.Afr.j. Biotechnol., 3(3): 182-185.
Muhammed.M., Oyebode T.S., Bello, A.H, and Bako, M.M. (2015).Mapping and identification of suitable dumping sites for solid waste management in Gwagwalada Area Council of the FCT, Nigeria.Journal of Environmental and Earth Science. 5: 17.
Mukhopadhyay, N and Ray,A.K. (2009). Effect of fermentation on the nutritive value of sesame seed meal in the diets of Rohu, labeo rohita (Hamilton) fingerlings. Aquacult. Nutr.,5 (4): 229-236.
Nneji, I. C., Oladipo, S.O., Nneji. L.M., Anifowoshe, A.T., Iyiola, O.A., Adeola, A.C. & Mustapha, M. K. (2018). Growth pattern and condition factor of seven freshwater fish species from Jebba Lake, north-central Nigeria. Iranian journal of ichthyology 5 (2): 167 – 172.
Olurin, K.B., Olojo, E. A. A and Olukoya, O.A (2006). Growth of African catfish, Clarias gariepinus fingerlings fed different level of cassava. International digital organization for scientific information. 1(1): 54 – 56.
Oluwatosin , O.O and Solomon, R.J. (2017). Growth performance of the African catfish (Clarias gariepinus) fed soaked ripe plantain peel meal (Musa paradisiaca). Direct research journal of Veterinary medicine and Animal Science. Vol 2 (2), pp. 55 – 65.
Onu, A. M., Idowu, R. T. and Dan-Kishiya, A. S. (2017). Gradual Replacement of Maize with Kunnu Waste in Diet for African Sharptooth Catfish Fingerlings Clarias
gariepinus (Siluriformes: Clariidae). BEST: Journal of Recent Trends in Natural Sciences Research & Development. 3 (1): 1-6.
Ponhigrahi ,S. and Powel, C.J. (2011). Effects of high rate of inclusion of palm kernel meal in broiler chick diets.Anim. Feed Sci. technol ., 34 (1): 37-47.
Ramachandran , S. , Barragi, A and Ray, A.K (2005). Improvement of nutritive value of grass pea (Lathyrus sativus) seed meal in formulated diets for Rohi, labeo rohita (Hamilton) fingerlings after fermentation with a fish gut bacterium. Bioresour. Technol.,96 (13): 1465-1472.
Ramachandran , S. and Ray, A.K (2007). Nutritional Evaluation of fermented black Grain (Phaseolusmungo) seed meal in compound diets for Rohi, labeo rohita(Hamilton) fingerlings.J. applied Ichthyol., 23 (1): 74-79.
Sogbesan , A.O and Ugwumba, A.A.A., (2006). Nutritional evaluation of termite (Macrotermes subhyalinus) meal as animal protein supplements in the diets of Heterobranchus longifilis. Turkish journal of fisheries and aquatic Sciences, 8 (1): 149-157.
Wishart, Skye. 2018."Second-rate grains" .New Zealand Geographic (152): 25
Published
How to Cite
Issue
Section
FUDMA Journal of Sciences
