THERAPEUTIC ACTIVITY OF AQUEOUS LEAF EXTRACT OF Phyllanthus niruri AGAINST Plasmodium falciparum

Aarthi, N. and Murugan,k. (2011). Antimalarial Activity and Phytochemical Screening of Ethanolic Leaf Extracts of Phyllanthus niruri and Mimosa pudica. Internationa Journal of Pharmaceutical Research and Development, 3(3): 198-205.

Adebisi, J.A., Okunloye, N.A., Togun,V.A. and Okwusidi, J.I. (2021).Evaluating in vivo antiplasmodial potency of aqueous leaf extract of phyllanthus niruri in swiss albino mice. European Journal of Biology and Medical Science Research, 9:10-21.

Ajala, T.O., Igwilo, C, I., Oregba, I. A. and Odeku, O. A. (2011). The antiplasmodial effect of the extracts and formulated capsules of phyllantus amarus on plasmodium yoelii infection in mice. Asian Pacific Journal of Tropical Medicine, 283-287.

Ansari A.S., Sevliya, K. Mohammad, I. Badar, A. and Lohiya, N.K. (2017). Plants for female fertility regulation: A Review. Journal of Pharmacology and Toxicology, 12:57-75.

Giribasu, N., Rao, P. V., Kumar, K. P., Muniandy, S., Rekha, S. S. and Salleh, N. (2014). Aqueous Extracts of Phyllanthus niruri Leaves Displays invitro Antioxidant Activity and Prevents Elevation of streptocin-induced Diabetic male rats. Retrieved from http://dx.doi.org/10.1155/2014/834815.

Government in Action (2005). Report from the presidential research and communication unit, office of public communication, State House, Abuja.

Htut, Z. W. (2009). Artemisinin Resistance in Plasmodium falciparum: Malaria. National English .Journal of Medicine, 361:1807-1808.

Kweyamba, P.A., Zofou, D., Efange, N., Assob, J-C.N., Kitau, J. and Nyindo, M. (2019). In vivo Studies on Antimalarial Activity of Commiphora africana and Dichrostachys cinerea use by the Maai in Arusha region,Tanzania. Malaria Journal, 18:119.

Lorke, D. (1983). A new approach for acute toxicity testing. Archive of Toxicology, 54: 275-289.

Nondo, R. S., Erasto, P. Moshi., M. J., Zacharia, A., Masimba, P.T. and Kidukuli, A. W. (2016). In vivo antimalaria activity of extracts of Tanzanian medicinal plants used for the treatment of malaria. Journal of Advance Pharmacology Technology Research, 7: 59-62.

Patel, J., Tripathi, P. Sharma, V. Chauhan, N. S. and Dixit, V. K. (2011). “Phylanthus amarus: Ethnomedical uses, phytochemistry and pharmacology: A review Journal Ethonopharmacology 138(2):286-313.

Rhiouani, H. El-Hilaly, J., Israili, Z. H and Lyoussi, B. (2008). Acute and sub-chronic toxicity of an aqueous extract of the leaves of Herniaria glabra in rodents. Journal of Ethnopharmacology, 118: 378–386.

Sendagire, H., Kyabayinze, D., Swedberg, G. Kironde, F. (2005). Plasmodium falciparum: Higher incidence of Molecular Resistance markers for Sulfodoxine than for Pyrimethamine in Kasangati, Uganda. Tropical Medicine for International Health, 10: 537-543.

Vermad, S. Sharma, H. and Garg, M. (2014). Phyllanthus amarus: A review. Journal of pharmacognosy and phytochemistry, 3(2):18-22.

World Health Organization (WHO), (2018). Malarial Report. http://apps.who.int/iris

World Health Organization (WHO), (2019). Malaria, https://www.who.int/news-room/fact-sheets/detal/malaria.

World Malaria Report, 2005. Information available to WHO and UNICEF at the end of 2004.